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The nootropic drugs--nootropil, aethimizol, diethylaminoethanol, and ambocarb diminished of amnesia of active avoidance habit evoked by maximal electroconvulsive shock in the rats. At the same time tested nootropic drugs potentiated the frog spinal motoneurons responses mediated by NMDA, but not non NMDA glutamate receptors activation. It was discussed the role of NMDA-potentiating nootropic drugs action in their anti-amnestic action.


I I Abramets, P V Andreev, I V Komissarov, I M Samoĭlovich, A V Titievskiĭ. Nootropic drugs potentiate nerve cell responses evoked by NMDA-glutamate receptor activation]. Biulleten' eksperimental'noĭ biologii i meditsiny. 1993 Jan;115(1):51-3

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PMID: 7914439

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