WF11899A, B and C, novel antifungal lipopeptides. I. Taxonomy, fermentation, isolation and physico-chemical properties.

T Iwamoto, A Fujie, K Sakamoto, Y Tsurumi, N Shigematsu, M Yamashita, S Hashimoto, M Okuhara, M Kohsaka

Exploratory Research Laboratories, Fujisawa Pharmaceutical Co., Ltd., Ibaraki, Japan.

The Journal of antibiotics 1994 Oct

filter terms:

WF11899A, B and C, novel antifungal lipopeptide anti biotics were isolated from the culture broth of Coleophoma empetri F-11899. These compounds belong to the echinocandin type of lipopeptides. Of these compounds, WF11899A showed good solubility in water. These three antibiotics possess potent in vitro antifungal activities against Candida spp.

Citation

T Iwamoto, A Fujie, K Sakamoto, Y Tsurumi, N Shigematsu, M Yamashita, S Hashimoto, M Okuhara, M Kohsaka. WF11899A, B and C, novel antifungal lipopeptides. I. Taxonomy, fermentation, isolation and physico-chemical properties. The Journal of antibiotics. 1994 Oct;47(10):1084-91