Clinical evaluation of Tc-99m cystine. A new renal radiopharmaceutical.

M Misra, B K Das, S Gambhir, B R Mittal, A B Sewatkar, S Ghosh, S N Banerjee

Department of Nuclear Medicine, Indian Institute of Chemical Biology, Calcutta.

Clinical nuclear medicine 1994 Apr

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Tc-99m cystine has been proved to be a good renal agent in animals. Its clinical evaluation has not been reported. In this study, Tc-99m cystine is used for evaluation of renal function in normal subjects and patients with chronic renal failure as well as in renal transplant patients. The results are compared with similar studies using Tc-99m DTPA and Tc-99m GHA. The clearance values also are compared with I-131 OIH. The results show that Tc-99m cystine has good radiopharmaceutical characteristics suitable for evaluation of both renal function as well as morphology.

Citation

M Misra, B K Das, S Gambhir, B R Mittal, A B Sewatkar, S Ghosh, S N Banerjee. Clinical evaluation of Tc-99m cystine. A new renal radiopharmaceutical. Clinical nuclear medicine. 1994 Apr;19(4):314-20