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Megakaryocytes in aspirates of normal and abnormal human bone marrow displayed rose-pink metachromasia when stained with a violet polymethine dye. The color of the megakaryocytes persisted when the stained sample was exposed to a dilute solution of sodium hypochlorite. Under the same conditions, other hematopoietic cells became colorless. This stain may be useful for demonstrating megakaryocyte from both healthy and diseased bone marrow specimens.


L Kass. A hypochlorite-fast metachromatic quick stain for human megakaryocytes. Biotechnic & histochemistry : official publication of the Biological Stain Commission. 1995 Jul;70(4):165-8

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PMID: 8580197

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