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Name: Cytochrome P-450 CYP27A1
Description: An NAPH-dependent cytochrome P450 enzyme that catalyzes the oxidation of the side chain of sterol intermediates such as the 27-hydroxylation of 5-beta-cholestane-3-alpha,7-alpha, 12-alpha-triol. Cytochrome P-450 CYP27A1 is a mitochondrial enzyme; however microsomal-derived homologs of the enzyme have been identified and are included under this heading.
Synonyms:
Cytochrome P 450 CYP27A1; Cytochrome P-450 Steroid 27-Hydroxylase; CYP27A1, Cytochrome P-450; Vitamin D3 25 Hydroxylase; Cytochrome P-450 CYP2R1; Cytochrome P-450 Sterol 26-Hydroxylase; Cytochrome P450, Family 27, Subfamily A, Polypeptide 1; Sterol 26 Hydroxylase; P450 CYP27, Cytochrome; Sterol 27 Hydroxylase.
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