QuickView for AAKG (gene)
- Gene Symbol:
- PRKAG2
Homo sapiens - Full name:
- protein kinase AMP-activated non-catalytic subunit gamma 2
- Synonyms:
- AAKG, AAKG2, CMH6, H91620p, WPWS, 5'-AMP-activated protein kinase subunit gamma-2, AMPK subunit gamma-2, protein kinase, AMP-activated, gamma 2 non-catalytic subunit
- Genomic Location:
- Chr 7: 150884133-151205249
- Description:
-
AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by i...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , Gallus gallus , Pan troglodytes , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
7q36.1
GO Molecular Function
protein kinase activator activity | kinase binding | ADP binding | phosphorylase kinase regulator activity | enzyme activator activity | protein kinase regulator activity | protein serine/threonine kinase inhibitor activity | cation binding | kinase regulator activity | protein kinase inhibitor activity | protein kinase binding | enzyme binding | ribonucleotide binding | nucleotide binding | enzyme inhibitor activity | carbohydrate derivative binding | protein serine/threonine kinase activity | molecular function regulator | catalytic activity | ATP binding | anion binding | AMP binding | adenyl nucleotide binding | AMP-activated protein kinase activity | purine nucleotide binding | ion binding | organic cyclic compound binding | cAMP-dependent protein kinase regulator activity | purine ribonucleoside triphosphate binding | protein binding | kinase inhibitor activity | kinase activator activity | transferase activity, transferring phosphorus-containing groups | cAMP-dependent protein kinase inhibitor activity | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | enzyme regulator activity | adenyl ribonucleotide binding | drug binding | kinase activity | heterocyclic compound binding | small molecule binding
GO Biological Process
negative regulation of phosphorylation | purine ribonucleotide metabolic process | purine ribonucleoside monophosphate biosynthetic process | protein kinase activator activity | phosphorylase kinase regulator activity | intracellular signal transduction | enzyme activator activity | regulation of localization | protein kinase regulator activity | macroautophagy | regulation of carbohydrate metabolic process | positive regulation of peptidyl-threonine phosphorylation | negative regulation of cellular process | negative regulation of kinase activity | protein serine/threonine kinase inhibitor activity | generation of precursor metabolites and energy | negative regulation of protein phosphorylation | positive regulation of phosphate metabolic process | sterol metabolic process | cellular process | regulation of glucose import | regulation of glycolytic process | nucleotide metabolic process | kinase regulator activity | protein kinase inhibitor activity | ribose phosphate metabolic process | purine nucleotide biosynthetic process | positive regulation of protein kinase activity | nucleoside triphosphate metabolic process | regulation of cell cycle | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | ribonucleotide metabolic process | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | catabolic process | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | cellular aromatic compound metabolic process | steroid biosynthetic process | cellular lipid metabolic process | response to stimulus | enzyme inhibitor activity | purine nucleotide metabolic process | monocarboxylic acid metabolic process | regulation of fatty acid biosynthetic process | positive regulation of protein metabolic process | cellular polysaccharide metabolic process | negative regulation of protein kinase activity | cellular nitrogen compound biosynthetic process | polysaccharide metabolic process | protein serine/threonine kinase activity | cellular nitrogen compound metabolic process | carbohydrate derivative biosynthetic process | negative regulation of metabolic process | protein modification process | cellular biosynthetic process | macromolecule modification | activation of protein kinase activity | molecular function regulator | nucleotide biosynthetic process | organic hydroxy compound metabolic process | ATP biosynthetic process | glycogen metabolic process | nitrogen compound metabolic process | negative regulation of phosphate metabolic process | negative regulation of catalytic activity | phosphorus metabolic process | ribonucleoside monophosphate biosynthetic process | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | lipid metabolic process | regulation of phosphorylation | cell cycle | AMP-activated protein kinase activity | organophosphate metabolic process | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | sterol biosynthetic process | regulation of nitrogen compound metabolic process | small molecule metabolic process | cellular carbohydrate metabolic process | negative regulation of protein serine/threonine kinase activity | regulation of fatty acid metabolic process | nucleobase-containing small molecule metabolic process | fatty acid biosynthetic process | biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | phosphorylation | purine ribonucleotide biosynthetic process | lipid biosynthetic process | carbohydrate metabolic process | nucleoside triphosphate biosynthetic process | protein phosphorylation | phosphate-containing compound metabolic process | autophagy | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | cAMP-dependent protein kinase regulator activity | regulation of protein metabolic process | regulation of protein phosphorylation | regulation of lipid biosynthetic process | drug metabolic process | carboxylic acid metabolic process | positive regulation of molecular function | protein metabolic process | positive regulation of protein modification process | cell cycle arrest | kinase inhibitor activity | regulation of kinase activity | kinase activator activity | metabolic process | cAMP-dependent protein kinase inhibitor activity | oxidation-reduction process | nucleobase-containing compound metabolic process | protein kinase activity | organic substance metabolic process | regulation of glucose transmembrane transport | negative regulation of cellular protein metabolic process | positive regulation of kinase activity | regulation of fatty acid oxidation | regulation of ATP metabolic process | regulation of phosphate metabolic process | fatty acid metabolic process | negative regulation of cell cycle | negative regulation of protein metabolic process | steroid metabolic process | negative regulation of molecular function | signaling | ribose phosphate biosynthetic process | energy reserve metabolic process | organic acid metabolic process | positive regulation of phosphorylation | cellular protein metabolic process | enzyme regulator activity | regulation of cellular ketone metabolic process | energy derivation by oxidation of organic compounds | kinase activity | cellular glucan metabolic process | cellular protein modification process | carbohydrate derivative metabolic process | regulation of transport | heterocycle metabolic process | regulation of generation of precursor metabolites and energy | regulation of lipid metabolic process | positive regulation of metabolic process | cellular metabolic process | ATP metabolic process | nucleoside monophosphate biosynthetic process | signal transduction | macromolecule metabolic process | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | catalytic complex | protein kinase complex | cell | nuclear lumen | cytoplasm | intracellular organelle | protein-containing complex | nucleoplasm | transferase complex | extracellular region | membrane-bounded organelle | nucleus | organelle | nucleotide-activated protein kinase complex | extracellular space | membrane-enclosed lumen | cytosol | intracellular
