QuickView for ACADL (gene)
- Gene Symbol:
- ACADL
Homo sapiens - Full name:
- acyl-CoA dehydrogenase long chain
- Synonyms:
- ACAD4, LCAD, long-chain specific acyl-CoA dehydrogenase, mitochondrial, acyl-Coenzyme A dehydrogenase, long chain
- Genomic Location:
- Chr 2: 210760959-210798392
- Description:
-
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are ...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
2q34
GO Molecular Function
cofactor binding | ribonucleotide binding | fatty-acyl-CoA binding | nucleotide binding | flavin adenine dinucleotide binding | coenzyme binding | carbohydrate derivative binding | catalytic activity | anion binding | adenyl nucleotide binding | acyl-CoA oxidase activity | amide binding | purine nucleotide binding | ion binding | palmitoyl-CoA oxidase activity | organic cyclic compound binding | purine ribonucleotide binding | adenyl ribonucleotide binding | acyl-CoA dehydrogenase activity | long-chain-acyl-CoA dehydrogenase activity | heterocyclic compound binding | oxidoreductase activity, acting on the CH-CH group of donors | oxidoreductase activity | small molecule binding
GO Biological Process
protein homooligomerization | negative regulation of cellular process | fatty acid beta-oxidation | cellular process | organic substance catabolic process | negative regulation of lipid biosynthetic process | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | catabolic process | cellular component organization | cellular lipid metabolic process | long-chain fatty acid catabolic process | monocarboxylic acid metabolic process | positive regulation of cold-induced thermogenesis | carnitine catabolic process | regulation of fatty acid biosynthetic process | carboxylic acid catabolic process | multicellular organismal homeostasis | fatty acid catabolic process | cellular nitrogen compound metabolic process | negative regulation of metabolic process | cellular component assembly | regulation of steroid metabolic process | nitrogen compound metabolic process | protein complex oligomerization | lipid metabolic process | amino-acid betaine metabolic process | acyl-CoA oxidase activity | negative regulation of fatty acid oxidation | small molecule metabolic process | protein homotetramerization | regulation of fatty acid metabolic process | carnitine metabolic process | regulation of cholesterol metabolic process | amino-acid betaine catabolic process | protein tetramerization | palmitoyl-CoA oxidase activity | cellular modified amino acid catabolic process | regulation of cellular metabolic process | cellular lipid catabolic process | fatty acid beta-oxidation using acyl-CoA dehydrogenase | lipid modification | homeostatic process | regulation of lipid biosynthetic process | long-chain fatty acid metabolic process | carboxylic acid metabolic process | protein-containing complex assembly | negative regulation of lipid metabolic process | metabolic process | oxidation-reduction process | lipid catabolic process | organic substance metabolic process | negative regulation of biosynthetic process | regulation of fatty acid oxidation | fatty acid metabolic process | lipid oxidation | temperature homeostasis | carnitine metabolic process, CoA-linked | organonitrogen compound catabolic process | organic acid metabolic process | regulation of cellular ketone metabolic process | acyl-CoA dehydrogenase activity | cellular modified amino acid metabolic process | long-chain-acyl-CoA dehydrogenase activity | fatty acid oxidation | regulation of lipid metabolic process | positive regulation of metabolic process | oxidoreductase activity, acting on the CH-CH group of donors | cellular metabolic process | oxidoreductase activity | negative regulation of fatty acid biosynthetic process | negative regulation of fatty acid metabolic process | multicellular organismal process
GO Cellular Component
mitochondrial matrix | intracellular membrane-bounded organelle | organelle membrane | cell | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | organelle | mitochondrial envelope | membrane-enclosed lumen | mitochondrial membrane | intracellular | membrane
