QuickView for ACADSB (gene)

Gene Symbol:

ACADSB Homo sapiens

Full name:

acyl-CoA dehydrogenase short/branched chain

Synonyms:

2-MEBCAD, ACAD7, SBCAD, short/branched chain specific acyl-CoA dehydrogenase, mitochondrial, 2-methyl branched chain acyl-CoA dehydrogenase, 2-methylbutyryl-coenzyme A dehydrogenase, acyl-Coenzyme A dehydrogenase, short/branched chain

Genomic Location:

Chr 10: 124758419-124807796

Description:

Short/branched chain acyl-CoA dehydrogenase(ACADSB) is a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. Substrate specificity is the primary characteristic used to define members of this gene family. The ACADSB gene prod...

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Short/branched chain acyl-CoA dehydrogenase(ACADSB) is a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. Substrate specificity is the primary characteristic used to define members of this gene family. The ACADSB gene product has the greatest activity towards the short branched chain acyl-CoA derivative, (S)-2-methylbutyryl-CoA, but also reacts significantly with other 2-methyl branched chain substrates and with short straight chain acyl-CoAs. The cDNA encodes for a mitochondrial precursor protein which is cleaved upon mitochondrial import and predicted to yield a mature peptide of approximately 43.7-KDa.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGIF_01 ,  TACTTGA_MIR26A_MIR26B ,  PAX8_01 ,  FAC1_01 ,  WTGAAAT_UNKNOWN ,  YAATNRNNNYNATT_UNKNOWN ,  PAX2_01 ,  CAGGTG_E12_Q6 ,  SP3_Q3 ,  MYOD_Q6 ,  GGGCGGR_SP1_Q6 ,  AHR_Q5 ,  S8_01 ,  MEIS1_01 ,  TAATTA_CHX10_01 ,  CART1_01 ,  TGACAGNY_MEIS1_01 ,  AAAGGAT_MIR501 ,  YNGTTNNNATT_UNKNOWN

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-26

Cytogenetic Map:

10q26.13

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