QuickView for ACKR2;jsessionid=E2C952D10CE563155FC10E4561189D28 (gene)

Gene Symbol:

ACKR2 Homo sapiens

Full name:

atypical chemokine receptor 2

Synonyms:

CCBP2, CCR10, CCR9, CMKBR9, D6, hD6, atypical chemokine receptor 2, C-C chemokine receptor D6, CC-chemokine-binding receptor JAB61, chemokine (C-C motif) receptor 9, chemokine (C-C) receptor 9, chemokine receptor CCR-10, chemokine receptor CCR-9, chemokine receptor D6, chemokine-binding protein 2, chemokine-binding protein D6

Genomic Location:

Chr 3: 42825968-42883779

Description:

This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells....

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This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Cytogenetic Map:

3p22.1

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