QuickView for ACSS2 (gene)

Gene Symbol:

ACSS2 Homo sapiens

Full name:

acyl-CoA synthetase short chain family member 2

Synonyms:

ACAS2, ACECS, ACS, ACSA, dJ1161H23.1, acetyl-coenzyme A synthetase, cytoplasmic, acetate thiokinase, acetate-CoA ligase, acetyl-Coenzyme A synthetase 2 (ADP forming), acyl-activating enzyme, cytoplasmic acetyl-coenzyme A synthetase

Genomic Location:

Chr 20: 32926406-32979423

Description:

This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate ge...

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This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Gallus gallus ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

IRF1_Q6 ,  AACTTT_UNKNOWN

Cytogenetic Map:

20q11.22

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