QuickView for ADAM28 (gene)

Gene Symbol:

ADAM28 Homo sapiens

Full name:

ADAM metallopeptidase domain 28

Synonyms:

ADAM 28, MDC-L, MDCL, eMDC II, eMDCII, disintegrin and metalloproteinase domain-containing protein 28, epididymal metalloproteinase-like, disintegrin-like, and cysteine-rich protein II, epididymial metalloproteinase-like, disintegrin-like, and cysteine-rich protein II, metalloproteinase-like, disintegrin-like, and cysteine-rich protein-L

Genomic Location:

Chr 8: 24207525-24268671

Description:

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development,...

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This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a lymphocyte-expressed ADAM protein. This gene is present in a gene cluster with other members of the ADAM family on chromosome 8. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus ,  Danio rerio ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

HP1SITEFACTOR_Q6 ,  ATCTTGC_MIR31 ,  RACCACAR_AML_Q6 ,  TTGTTT_FOXO4_01

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-299

Cytogenetic Map:

8p21.2

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