QuickView for ADCY8;jsessionid=E7B5DB9477979439F1C8BE0276B24088 (gene)
- Gene Symbol:
- ADCY8
Homo sapiens - Full name:
- adenylate cyclase 8
- Synonyms:
- AC8, ADCY3, HBAC1, adenylate cyclase type 8, ATP pyrophosphate-lyase 8, HEL-S-172mP, adenylate cyclase 8 (brain), adenylate cyclase type VIII, adenylyl cyclase 8, adenylyl cyclase-8, brain, ca(2+)/calmodulin-activated adenylyl cyclase, epididymis secretory sperm binding protein Li 172mP
- Genomic Location:
- Chr 8: 131861729-132123854
- Description:
-
Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G protein...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
8q24.22
GO Molecular Function
cation binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | lyase activity | adenylate cyclase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | calcium- and calmodulin-responsive adenylate cyclase activity | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | phosphorus-oxygen lyase activity | metal ion binding | heterocyclic compound binding | small molecule binding | cyclase activity
GO Biological Process
purine ribonucleotide metabolic process | cyclic nucleotide biosynthetic process | long-term memory | intracellular signal transduction | response to hormone | renal water homeostasis | cellular process | nucleotide metabolic process | cAMP biosynthetic process | ribose phosphate metabolic process | purine nucleotide biosynthetic process | ribonucleotide metabolic process | response to peptide hormone | regulation of cellular process | organic cyclic compound metabolic process | cellular response to organonitrogen compound | cellular aromatic compound metabolic process | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | response to stimulus | purine nucleotide metabolic process | cellular nitrogen compound biosynthetic process | cyclic purine nucleotide metabolic process | multicellular organismal homeostasis | response to peptide | cellular nitrogen compound metabolic process | carbohydrate derivative biosynthetic process | G-protein coupled receptor signaling pathway | cellular biosynthetic process | nucleotide biosynthetic process | water homeostasis | response to nitrogen compound | cellular response to hormone stimulus | nitrogen compound metabolic process | cellular response to peptide hormone stimulus | phosphorus metabolic process | learning or memory | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | adenylate cyclase-activating G-protein coupled receptor signaling pathway | cyclic nucleotide metabolic process | nervous system process | cellular response to peptide | organophosphate metabolic process | small molecule metabolic process | nucleobase-containing small molecule metabolic process | second-messenger-mediated signaling | cognition | biosynthetic process | aromatic compound biosynthetic process | purine ribonucleotide biosynthetic process | phosphate-containing compound metabolic process | cell communication | cyclic-nucleotide-mediated signaling | homeostatic process | cAMP metabolic process | response to glucagon | response to organic substance | cAMP-mediated signaling | metabolic process | regulation of body fluid levels | chemical homeostasis | behavior | nucleobase-containing compound metabolic process | organic substance metabolic process | renal system process | memory | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | signaling | ribose phosphate biosynthetic process | carbohydrate derivative metabolic process | multicellular organismal water homeostasis | response to organonitrogen compound | heterocycle metabolic process | cellular metabolic process | cellular response to organic substance | cellular response to glucagon stimulus | signal transduction | multicellular organismal process
GO Cellular Component
integral component of membrane | cell | intrinsic component of membrane | plasma membrane | integral component of plasma membrane | cell periphery | membrane | intrinsic component of plasma membrane
