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QuickView for ADGRB3 (gene)


Gene Symbol:
ADGRB3 Homo sapiens Homo sapiens
Full name:
adhesion G protein-coupled receptor B3
Synonyms:
BAI3, adhesion G protein-coupled receptor B3, brain-specific angiogenesis inhibitor 3, dJ91B17.1 (brain-specific angiogenesis inhibitor 3)
Genomic Location:
Chr 6: 69402353-70156124
Description:
This p53-target gene encodes a brain-specific angiogenesis inhibitor, a seven-span transmembrane protein, and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities, and may also play a role in angiogenesis.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
ATGCAGT_MIR217 RTAAACA_FREAC2_01 FREAC7_01 TGIF_01 FOXJ2_02 RSRFC4_01 TGAATGT_MIR181A_MIR181B_MIR181C_MIR181D HFH3_01 SREBP1_02 AP3_Q6
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 6
6q12-q13





GO Molecular Function

enzyme activator activity | GTPase activator activity | transmembrane signaling receptor activity | G-protein coupled receptor activity | GTPase regulator activity | molecular function regulator | signaling receptor activity | protein binding | enzyme regulator activity

GO Biological Process

myoblast fusion | positive regulation of cellular component organization | regulation of cell morphogenesis | regulation of neurogenesis | intracellular signal transduction | enzyme activator activity | regulation of synapse assembly | regulation of cell development | syncytium formation by plasma membrane fusion | positive regulation of developmental process | cell differentiation | nervous system development | neurogenesis | generation of neurons | positive regulation of GTPase activity | cellular process | cell maturation | neuron development | GTPase activator activity | learning | positive regulation of catalytic activity | regulation of neuron projection development | regulation of cell differentiation | muscle structure development | muscle cell differentiation | regulation of angiogenesis | regulation of cellular process | cellular component organization | G-protein coupled receptor activity | regulation of vasculature development | response to stimulus | GTPase regulator activity | negative regulation of angiogenesis | G-protein coupled receptor signaling pathway | regulation of synapse structure or activity | molecular function regulator | system development | multicellular organism development | syncytium formation | learning or memory | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | adenylate cyclase-activating G-protein coupled receptor signaling pathway | regulation of catalytic activity | regulation of neuron differentiation | nervous system process | maintenance of synapse structure | regulation of synapse organization | synapse organization | positive regulation of hydrolase activity | second-messenger-mediated signaling | cognition | neuron remodeling | regulation of GTPase activity | cell communication | cyclic-nucleotide-mediated signaling | positive regulation of synapse assembly | striated muscle cell differentiation | motor learning | neuron maturation | positive regulation of molecular function | neuron differentiation | regulation of cell morphogenesis involved in differentiation | cAMP-mediated signaling | anatomical structure development | regulation of dendrite morphogenesis | cell surface receptor signaling pathway | cellular component maintenance | developmental maturation | behavior | positive regulation of cellular component biogenesis | anatomical structure formation involved in morphogenesis | regulation of dendrite development | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | signaling | myotube differentiation | cell development | enzyme regulator activity | anatomical structure morphogenesis | regulation of nervous system development | regulation of developmental process | developmental process | negative regulation of vasculature development | regulation of cell projection organization | regulation of cellular component organization | signal transduction | multicellular organismal process

GO Cellular Component

synaptic cleft | integral component of membrane | synapse | cell | intrinsic component of membrane | postsynapse | plasma membrane | integral component of plasma membrane | extracellular region | cell periphery | membrane | intrinsic component of plasma membrane