QuickView for ADGRG1;jsessionid=DBFC9236E4F64F2EC244BD08ED097310 (gene)

Gene Symbol:

ADGRG1 Homo sapiens

Full name:

adhesion G protein-coupled receptor G1

Synonyms:

BFPP, BPPR, GPR56, TM7LN4, TM7XN1, adhesion G-protein coupled receptor G1, G-protein coupled receptor 56, 7-transmembrane protein with no EGF-like N-terminal domains-1, G protein-coupled receptor 56, testicular tissue protein Li 77

Genomic Location:

Chr 16: 56211459-56256445

Description:

This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontopa...

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This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGANTCA_AP1_C ,  ATF4_Q2 ,  GGGAGGRR_MAZ_Q6 ,  BACH2_01 ,  RNGTGGGC_UNKNOWN ,  BACH1_01 ,  RGAGGAARY_PU1_Q6

Cytogenetic Map:

16q21

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