QuickView for ADGRL2;jsessionid=7D79063078F252A7A5FB4215C87122CD (gene)

Gene Symbol:

ADGRL2 Homo sapiens

Full name:

adhesion G protein-coupled receptor L2

Synonyms:

CIRL2, CL2, LEC1, LPHH1, LPHN2, adhesion G protein-coupled receptor L2, calcium-independent alpha-latrotoxin receptor 2, latrophilin homolog 1, latrophilin-2, lectomedin-1

Genomic Location:

Chr 1: 82038670-82230695

Description:

This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors. The encoded protein participates in the regulation of exocytosis. The proprotein is thought to be further cleaved within a cysteine-rich G-protein-coupled receptor proteolysis site into two chains that are non-covalently bound at the cell membrane. Alternative s...

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This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors. The encoded protein participates in the regulation of exocytosis. The proprotein is thought to be further cleaved within a cysteine-rich G-protein-coupled receptor proteolysis site into two chains that are non-covalently bound at the cell membrane. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  C. elegans ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AACWWCAANK_UNKNOWN ,  HNF4ALPHA_Q6 ,  GTATTAT_MIR3693P ,  TGANTCA_AP1_C ,  TAL1ALPHAE47_01 ,  TTANTCA_UNKNOWN ,  FOXO4_01 ,  IPF1_Q4 ,  MEIS1BHOXA9_01 ,  CTTTGA_LEF1_Q2 ,  CTTTGTA_MIR524 ,  CDP_02 ,  LEF1_Q2 ,  GGATTA_PITX2_Q2 ,  GCTCTTG_MIR335 ,  ATTCTTT_MIR186 ,  CDPCR3_01 ,  PITX2_Q2 ,  NKX25_02 ,  FOXO1_01 ,  TGTTTGY_HNF3_Q6 ,  MEIS1AHOXA9_01 ,  AATGTGA_MIR23A_MIR23B ,  GGCACTT_MIR519E ,  TTGCCAA_MIR182 ,  TTGTTT_FOXO4_01 ,  TAL1BETAITF2_01 ,  E2F_Q2 ,  CTTTGT_LEF1_Q2 ,  MMEF2_Q6 ,  ZF5_B ,  SRY_02 ,  AACTTT_UNKNOWN ,  CRX_Q4 ,  TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497 ,  PAX2_02 ,  HNF4_01_B ,  HNF6_Q6 ,  TATTATA_MIR374

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-15 ,  Predicted Gene Targets for miR-19 ,  Predicted Gene Targets for miR-194 ,  Predicted Gene Targets for miR-23 ,  Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-323 ,  Predicted Gene Targets for miR-335 ,  Predicted Gene Targets for miR-369-3p ,  Predicted Gene Targets for miR-370 ,  Predicted Gene Targets for miR-381 ,  Predicted Gene Targets for miR-433-3p ,  Predicted Gene Targets for miR-96 ,  Predicted Gene Targets for miR-182 ,  Predicted Gene Targets for miR-374 ,  Predicted Gene Targets for miR-410 ,  Predicted Gene Targets for miR-493-5p ,  Predicted Gene Targets for miR-495

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Cytogenetic Map:

1p31.1

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