Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for ADI1;jsessionid=FD07765C48EA2C1A1337DBD0E62C42A3 (gene)


Gene Symbol:
ADI1 Homo sapiens Homo sapiens
Full name:
acireductone dioxygenase 1
Synonyms:
APL1, ARD, Fe-ARD, HMFT1638, MTCBP1, Ni-ARD, SIPL, mtnD, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, MT1-MMP cytoplasmic tail-binding protein-1, acireductone dioxygenase (Fe(2+)-requiring), acireductone dioxygenase (Ni(2+)-requiring), membrane-type 1 matrix metalloproteinase cytoplasmic tail binding protein-1, submergence induced protein 2, submergence-induced protein-like factor
Genomic Location:
Chr 2: 3480698-3502306
Description:
This gene encodes an enzyme that belongs to the aci-reductone dioxygenase family of metal-binding enzymes, which are involved in methionine salvage. This enzyme may regulate mRNA processing in the nucleus, and may carry out different functions depending on its localization. Related pseudogenes have been defined on chromosomes 8 and 20. Alternative ...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Gallus gallus Danio rerio Canis lupus familiaris Bos taurus Pan troglodytes
External Links:
Entrez Gene
Cytogenetic Map:
chr 2
2p25.3





GO Molecular Function

cation binding | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | acireductone dioxygenase [iron(II)-requiring] activity | catalytic activity | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen | ion binding | protein binding | dioxygenase activity | metal ion binding | oxidoreductase activity

GO Biological Process

sulfur compound metabolic process | cellular process | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | sulfur amino acid biosynthetic process | L-methionine salvage | cellular amino acid metabolic process | acireductone dioxygenase [iron(II)-requiring] activity | cellular amino acid biosynthetic process | cellular biosynthetic process | sulfur amino acid metabolic process | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen | nitrogen compound metabolic process | small molecule metabolic process | methionine metabolic process | biosynthetic process | drug metabolic process | carboxylic acid metabolic process | methionine biosynthetic process | metabolic process | oxidation-reduction process | organic substance metabolic process | dioxygenase activity | L-methionine salvage from methylthioadenosine | organic acid metabolic process | cellular metabolic process | oxidoreductase activity

GO Cellular Component

intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | plasma membrane | membrane-bounded organelle | nucleus | organelle | cell periphery | cytosol | intracellular | membrane