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QuickView for ADIPOQ (gene)


Gene Symbol:
ADIPOQ Homo sapiens Homo sapiens
Full name:
adiponectin, C1Q and collagen domain containing
Synonyms:
ACDC, ACRP30, ADIPQTL1, ADPN, APM-1, APM1, GBP28, adiponectin, 30 kDa adipocyte complement-related protein, adipocyte complement-related 30 kDa protein, adipose most abundant gene transcript 1 protein, adipose specific collagen-like factor, gelatin-binding protein 28
Genomic Location:
Chr 3: 188043157-188058946
Description:
This gene is expressed in adipose tissue exclusively. It encodes a protein with similarity to collagens X and VIII and complement factor C1q. The encoded protein circulates in the plasma and is involved with metabolic and hormonal processes. Mutations in this gene are associated with adiponectin deficiency. Multiple alternatively spliced variants, ...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Canis lupus familiaris Gallus gallus Pan troglodytes Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 3
3q27.3


Transcripts Names
NM_004797
NM_001177800
Protein Names
Q15848
B2R773
A8K660
Q58EX9



GO Molecular Function

carboxylic acid binding | signaling receptor binding | sialic acid binding | carbohydrate derivative binding | hormone activity | molecular function regulator | anion binding | identical protein binding | ion binding | protein binding | protein homodimerization activity | receptor regulator activity | protein dimerization activity | receptor ligand activity | cytokine activity | organic acid binding | small molecule binding

GO Biological Process

positive regulation of myeloid cell apoptotic process | response to extracellular stimulus | regulation of ERK1 and ERK2 cascade | negative regulation of phosphorylation | protein homooligomerization | regulation of epithelial cell differentiation involved in kidney development | negative regulation of intracellular transport | regulation of intracellular protein transport | response to nutrient levels | negative regulation of MAPK cascade | negative regulation of immune system process | response to cytokine | protein localization to cell periphery | regulation of cellular localization | regulation of cholesterol transport | positive regulation of apoptotic process | regulation of cell development | negative regulation of low-density lipoprotein particle receptor biosynthetic process | regulation of localization | regulation of carbohydrate metabolic process | regulation of programmed cell death | positive regulation of peptidyl-tyrosine phosphorylation | negative regulation of phagocytosis | regulation of immune system process | response to hormone | negative regulation of cellular process | negative regulation of kinase activity | positive regulation of developmental process | fatty acid beta-oxidation | regulation of MAP kinase activity | negative regulation of RNA biosynthetic process | glucose metabolic process | cell differentiation | negative regulation of fat cell differentiation | response to drug | generation of precursor metabolites and energy | negative regulation of protein phosphorylation | glucose homeostasis | positive regulation of phosphate metabolic process | negative regulation of metanephric mesenchymal cell migration | cellular response to epinephrine stimulus | response to antibiotic | negative regulation of DNA metabolic process | regulation of lipid transport | response to organophosphorus | cellular process | negative regulation of DNA biosynthetic process | positive regulation of glomerulus development | organic substance catabolic process | negative regulation of inflammatory response | regulation of glucose import | regulation of cell motility | localization | positive regulation of protein kinase A signaling | response to linoleic acid | negative regulation of smooth muscle cell migration | negative regulation of signaling | negative regulation of gluconeogenesis | positive regulation of cholesterol efflux | regulation of embryonic development | negative regulation of tumor necrosis factor-mediated signaling pathway | negative regulation of nucleic acid-templated transcription | protein heterotrimerization | positive regulation of protein kinase activity | macromolecule localization | regulation of response to cytokine stimulus | negative regulation of secretion | response to hypoxia | negative regulation of platelet-derived growth factor receptor-alpha signaling pathway | positive regulation of catalytic activity | regulation of myeloid cell differentiation | positive regulation of nitrogen compound metabolic process | negative regulation of cell migration | brown fat cell differentiation | negative regulation of hormone secretion | negative regulation of establishment of protein localization | negative regulation of cellular metabolic process | response to peptide hormone | regulation of binding | regulation of fat cell differentiation | regulation of myeloid leukocyte differentiation | regulation of cell differentiation | negative regulation of receptor biosynthetic process | negative regulation of cell motility | positive regulation of interleukin-8 production | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | catabolic process | negative regulation of granulocyte differentiation | negative regulation of tumor necrosis factor production | positive regulation of cellular protein metabolic process | negative regulation of protein autophosphorylation | cellular response to organonitrogen compound | negative regulation of receptor binding | cellular component organization | cellular lipid metabolic process | urogenital system development | response to stimulus | negative regulation of protein transport | regulation of platelet-derived growth factor receptor-alpha signaling pathway | regulation of cellular protein localization | monocarboxylic acid metabolic process | positive regulation of cold-induced thermogenesis | regulation of macrophage derived foam cell differentiation | regulation of fatty acid biosynthetic process | regulation of peptidyl-tyrosine phosphorylation | positive regulation of protein metabolic process | negative regulation of cell adhesion | carboxylic acid catabolic process | detection of oxidative stress | negative regulation of intracellular protein transport | response to stress | regulation of heterotypic cell-cell adhesion | negative regulation of tumor necrosis factor superfamily cytokine production | negative regulation of protein kinase activity | regulation of cell proliferation | regulation of granulocyte differentiation | regulation of plasma lipoprotein particle levels | response to peptide | positive regulation of glucose import | circadian rhythm | response to glucose | regulation of epithelial cell differentiation | regulation of smooth muscle cell migration | cellular localization | response to alcohol | fatty acid catabolic process | rhythmic process | negative regulation of transport | cellular response to organic cyclic compound | hormone activity | regulation of phagocytosis | regulation of protein transport | blood circulation | regulation of glycogen (starch) synthase activity | negative regulation of metabolic process | positive regulation of protein serine/threonine kinase activity | cellular component assembly | negative regulation of hemopoiesis | regulation of peptide transport | modulation of chemical synaptic transmission | regulation of cell adhesion | kidney development | negative regulation of ERK1 and ERK2 cascade | regulation of intracellular transport | molecular function regulator | negative regulation of blood pressure | response to ethanol | regulation of nucleic acid-templated transcription | response to nitrogen compound | cellular response to hormone stimulus | response to external biotic stimulus | system development | response to oxygen levels | regulation of signal transduction | negative regulation of secretion by cell | negative regulation of phosphate metabolic process | multicellular organism development | negative regulation of catalytic activity | response to activity | cellular response to peptide hormone stimulus | regulation of MAPK cascade | response to purine-containing compound | response to fatty acid | protein complex oligomerization | cellular response to insulin stimulus | negative regulation of cold-induced thermogenesis | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | lipid metabolic process | regulation of phosphorylation | negative regulation of cellular protein localization | regulation of hormone levels | regulation of hormone secretion | protein localization to plasma membrane | regulation of gene expression | protein localization to membrane | response to lipid | cellular response to peptide | regulation of blood pressure | regulation of protein autophosphorylation | positive regulation of renal albumin absorption | response to epinephrine | negative regulation of cytokine production | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | negative regulation of smooth muscle cell proliferation | negative regulation of myeloid cell differentiation | regulation of platelet-derived growth factor receptor signaling pathway | regulation of nitrogen compound metabolic process | regulation of cell migration | monosaccharide metabolic process | small molecule metabolic process | positive regulation of intracellular signal transduction | negative regulation of protein serine/threonine kinase activity | response to corticosteroid | regulation of cellular component movement | response to nutrient | fat cell differentiation | response to oxidative stress | negative regulation of binding | regulation of fatty acid metabolic process | negative regulation of heterotypic cell-cell adhesion | positive regulation of cell differentiation | positive regulation of cholesterol transport | regulation of cAMP-dependent protein kinase activity | positive regulation of glucose transmembrane transport | negative regulation of vascular associated smooth muscle cell migration | regulation of cellular protein metabolic process | positive regulation of monocyte chemotactic protein-1 production | carbohydrate metabolic process | positive regulation of chemokine production | response to toxic substance | positive regulation of lipid localization | regulation of tumor necrosis factor production | positive regulation of glycogen (starch) synthase activity | plasma lipoprotein particle clearance | cellular response to drug | response to bacterium | negative regulation of cell-cell adhesion | negative regulation of protein binding | regulation of cellular metabolic process | regulation of protein kinase activity | protein trimerization | metanephros development | negative regulation of macrophage differentiation | cellular lipid catabolic process | response to catecholamine | regulation of tumor necrosis factor-mediated signaling pathway | regulation of protein metabolic process | positive regulation of signal transduction | lipid modification | homeostatic process | response to monosaccharide | regulation of protein phosphorylation | regulation of cytokine-mediated signaling pathway | regulation of locomotion | negative regulation of MAP kinase activity | regulation of RNA metabolic process | renal system development | negative regulation of vascular smooth muscle cell proliferation | positive regulation of transport | regulation of lipid biosynthetic process | positive regulation of metanephric glomerular visceral epithelial cell development | carboxylic acid metabolic process | positive regulation of molecular function | regulation of signaling receptor activity | response to monoamine | receptor regulator activity | protein-containing complex assembly | negative regulation of carbohydrate metabolic process | regulation of establishment of protein localization | positive regulation of protein modification process | response to organic substance | regulation of hemopoiesis | regulation of kinase activity | positive regulation of fatty acid metabolic process | positive regulation of metanephric glomerulus development | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | response to insulin | anatomical structure development | negative regulation of response to cytokine stimulus | regulation of glucose metabolic process | negative regulation of endocytosis | metabolic process | positive regulation of cell development | regulation of receptor biosynthetic process | negative regulation of I-kappaB kinase/NF-kappaB signaling | positive regulation of cAMP-dependent protein kinase activity | regulation of RNA biosynthetic process | hexose metabolic process | oxidation-reduction process | negative regulation of transcription, DNA-templated | cellular protein localization | regulation of cell-cell adhesion involved in gastrulation | regulation of vesicle-mediated transport | response to sucrose | chemical homeostasis | regulation of secretion | positive regulation of cell death | regulation of myeloid cell apoptotic process | receptor ligand activity | lipid catabolic process | cytokine activity | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | regulation of glucose transmembrane transport | animal organ development | negative regulation of cellular protein metabolic process | negative regulation of cellular component movement | positive regulation of programmed cell death | positive regulation of kinase activity | cellular response to cAMP | regulation of phosphate metabolic process | fatty acid metabolic process | positive regulation of cytokine production | response to cAMP | lipid oxidation | regulation of protein kinase A signaling | negative regulation of protein metabolic process | negative regulation of macrophage derived foam cell differentiation | regulation of cell communication | regulation of macrophage differentiation | negative regulation of molecular function | negative regulation of signal transduction | positive regulation of I-kappaB kinase/NF-kappaB signaling | regulation of transcription, DNA-templated | regulation of protein binding | response to organic cyclic compound | regulation of endocytosis | protein localization | organic acid metabolic process | positive regulation of phosphorylation | regulation of cytokine production | protein heterooligomerization | cellular macromolecule localization | response to biotic stimulus | regulation of cellular ketone metabolic process | regulation of developmental process | regulation of cholesterol efflux | developmental process | regulation of DNA biosynthetic process | positive regulation of epithelial cell differentiation | regulation of monocyte chemotactic protein-1 production | regulation of chemokine production | regulation of gastrulation | regulation of transport | negative regulation of cell proliferation | regulation of cell-cell adhesion | positive regulation of kidney development | response to organonitrogen compound | negative regulation of cytokine-mediated signaling pathway | negative regulation of synaptic transmission | regulation of gluconeogenesis | fatty acid oxidation | regulation of lipid metabolic process | positive regulation of metabolic process | positive regulation of lipid metabolic process | positive regulation of lipid transport | cellular metabolic process | negative regulation of platelet-derived growth factor receptor signaling pathway | response to tumor necrosis factor | cellular response to organic substance | regulation of protein localization | regulation of cell death | regulation of smooth muscle cell proliferation | response to carbohydrate | low-density lipoprotein particle clearance | response to steroid hormone | regulation of inflammatory response | carbohydrate homeostasis | negative regulation of locomotion | negative regulation of myeloid leukocyte differentiation | regulation of I-kappaB kinase/NF-kappaB signaling | negative regulation of cell differentiation | regulation of cellular component organization | response to other organism | positive regulation of signaling | cellular response to catecholamine stimulus | regulation of low-density lipoprotein particle receptor biosynthetic process | regulation of signaling | response to glucocorticoid | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | protein-containing complex | endomembrane system | collagen trimer | extracellular region | membrane-bounded organelle | organelle | extracellular space | cell surface | intracellular