QuickView for AIF (gene)
- Gene Symbol:
- Aifm1
Mus musculus - Full name:
- apoptosis-inducing factor, mitochondrion-associated 1
- Synonyms:
- AIF, AIFsh2, Hq, Pdcd8, apoptosis-inducing factor 1, mitochondrial, harlequin, programmed cell death protein 8
- Genomic Location:
- Chr X: 45828121-45866603
- Orthologs:
- Homo sapiens , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Danio rerio , Gallus gallus , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
oxidoreductase activity, acting on NAD(P)H | cofactor binding | oxidoreductase activity, acting on the CH-NH group of donors | nucleic acid binding | nucleotide binding | flavin adenine dinucleotide binding | coenzyme binding | catalytic activity | anion binding | electron transfer activity | DNA binding | electron-transferring-flavoprotein dehydrogenase activity | ion binding | organic cyclic compound binding | protein binding | FAD binding | protein dimerization activity | NAD(P)H oxidase activity | oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor | heterocyclic compound binding | oxidoreductase activity | small molecule binding
GO Biological Process
oxidoreductase activity, acting on NAD(P)H | regulation of cysteine-type endopeptidase activity | response to endoplasmic reticulum stress | intracellular signal transduction | positive regulation of apoptotic process | regulation of programmed cell death | neuron death | cell differentiation | nervous system development | generation of precursor metabolites and energy | neurogenesis | generation of neurons | regulation of neuron death | cellular process | oxidoreductase activity, acting on the CH-NH group of donors | cellular respiration | regulation of proteolysis | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | intrinsic apoptotic signaling pathway | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | positive regulation of cellular protein metabolic process | mitochondrial respiratory chain complex assembly | cellular component organization | response to stimulus | positive regulation of protein metabolic process | positive regulation of peptidase activity | response to stress | mitochondrial respiratory chain complex I assembly | electron transport chain | positive regulation of cysteine-type endopeptidase activity | programmed cell death | positive regulation of proteolysis | apoptotic mitochondrial changes | cellular component assembly | mitochondrion organization | apoptotic process | system development | multicellular organism development | regulation of peptidase activity | regulation of catalytic activity | electron transfer activity | cellular response to stress | positive regulation of cellular metabolic process | NADH dehydrogenase complex assembly | regulation of nitrogen compound metabolic process | neuron apoptotic process | regulation of cysteine-type endopeptidase activity involved in apoptotic process | electron-transferring-flavoprotein dehydrogenase activity | response to oxidative stress | positive regulation of hydrolase activity | regulation of cellular protein metabolic process | positive regulation of endopeptidase activity | cellular protein-containing complex assembly | positive regulation of neuron death | regulation of apoptotic DNA fragmentation | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | cell communication | regulation of cellular metabolic process | regulation of neuron apoptotic process | regulation of protein metabolic process | apoptotic signaling pathway | positive regulation of molecular function | neuron differentiation | protein-containing complex assembly | positive regulation of neuron apoptotic process | anatomical structure development | metabolic process | activation of cysteine-type endopeptidase activity involved in apoptotic process | oxidation-reduction process | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | positive regulation of cell death | cell death | positive regulation of programmed cell death | signaling | regulation of endopeptidase activity | energy derivation by oxidation of organic compounds | developmental process | organelle organization | NAD(P)H oxidase activity | positive regulation of metabolic process | oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor | regulation of execution phase of apoptosis | cellular metabolic process | regulation of cell death | oxidoreductase activity | regulation of cellular component organization | signal transduction | multicellular organismal process | respiratory electron transport chain
GO Cellular Component
mitochondrial intermembrane space | organelle inner membrane | intracellular membrane-bounded organelle | mitochondrial inner membrane | organelle membrane | cell | organelle outer membrane | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | nucleus | organelle | mitochondrial outer membrane | mitochondrial envelope | membrane-enclosed lumen | outer membrane | mitochondrial membrane | cytosol | intracellular | membrane
