QuickView for AKAP10 (gene)

Gene Symbol:

AKAP10 Homo sapiens

Full name:

A-kinase anchoring protein 10

Synonyms:

AKAP-10, D-AKAP-2, D-AKAP2, PRKA10, A-kinase anchor protein 10, mitochondrial, A kinase (PRKA) anchor protein 10, A kinase anchor protein 10, dual specificity A kinase-anchoring protein 2, mitochondrial A kinase PPKA anchor protein 10, protein kinase A anchoring protein 10

Genomic Location:

Chr 17: 19749341-19821721

Description:

This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins bind to the regulatory subunits of protein kinase A (PKA) and confine the holoenzyme to discrete locations within the cell. The encoded protein is localized to mitochondria and interacts with both the type I and type II regulatory subunits of PKA. Polymorphis...

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This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins bind to the regulatory subunits of protein kinase A (PKA) and confine the holoenzyme to discrete locations within the cell. The encoded protein is localized to mitochondria and interacts with both the type I and type II regulatory subunits of PKA. Polymorphisms in this gene may be associated with increased risk of arrhythmias and sudden cardiac death.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus ,  Danio rerio ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

USF_Q6 ,  ARNT_01 ,  FOXO4_01 ,  YTATTTTNR_MEF2_02 ,  CACGTG_MYC_Q2 ,  GGGACCA_MIR133A_MIR133B ,  EGR2_01 ,  USF_01 ,  RNGTGGGC_UNKNOWN ,  NMYC_01 ,  SCGGAAGY_ELK1_02 ,  TAANNYSGCG_UNKNOWN

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-133 ,  Predicted Gene Targets for miR-155

Cytogenetic Map:

17p11.2

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