QuickView for ALDH1A1 (gene)
- Gene Symbol:
- ALDH1A1
Homo sapiens - Full name:
- aldehyde dehydrogenase 1 family member A1
- Synonyms:
- ALDC, ALDH-E1, ALDH1, ALDH11, HEL-9, HEL-S-53e, HEL12, PUMB1, RALDH1, retinal dehydrogenase 1, ALDH class 1, ALHDII, RALDH 1, acetaldehyde dehydrogenase 1, aldehyde dehydrogenase 1, soluble, aldehyde dehydrogenase, liver cytosolic, epididymis luminal protein 12, epididymis luminal protein 9, epididymis secretory sperm binding protein Li 53e, retinaldehyde dehydrogenase 1
- Genomic Location:
- Chr 9: 74705407-74757789
- Description:
-
The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished ...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Bos taurus , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
9q21.13
GO Molecular Function
enzyme activator activity | cofactor binding | androgen binding | GTPase activator activity | nucleotide binding | coenzyme binding | GTPase regulator activity | molecular function regulator | catalytic activity | organic cyclic compound binding | hormone binding | retinal dehydrogenase activity | benzaldehyde dehydrogenase (NAD+) activity | aldehyde dehydrogenase (NAD) activity | NAD binding | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | enzyme regulator activity | heterocyclic compound binding | oxidoreductase activity | small molecule binding
GO Biological Process
enzyme activator activity | generation of precursor metabolites and energy | positive regulation of GTPase activity | cellular process | organic substance catabolic process | GTPase activator activity | ethanol metabolic process | positive regulation of catalytic activity | carbohydrate catabolic process | regulation of metabolic process | catabolic process | cellular lipid metabolic process | GTPase regulator activity | alcohol metabolic process | retinol metabolic process | negative regulation of metabolic process | fructose metabolic process | molecular function regulator | organic hydroxy compound metabolic process | retinoid metabolic process | antibiotic metabolic process | phosphorus metabolic process | negative regulation of cold-induced thermogenesis | regulation of catalytic activity | lipid metabolic process | regulation of hormone levels | organophosphate metabolic process | monosaccharide metabolic process | small molecule metabolic process | positive regulation of hydrolase activity | carbohydrate metabolic process | regulation of GTPase activity | phosphate-containing compound metabolic process | ethanol oxidation | glyceraldehyde-3-phosphate metabolic process | drug metabolic process | positive regulation of molecular function | cellular aldehyde metabolic process | retinal dehydrogenase activity | benzaldehyde dehydrogenase (NAD+) activity | aldehyde dehydrogenase (NAD) activity | metabolic process | hexose metabolic process | oxidation-reduction process | fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | organic substance metabolic process | diterpenoid metabolic process | enzyme regulator activity | hormone metabolic process | isoprenoid metabolic process | carbohydrate derivative metabolic process | cellular metabolic process | oxidoreductase activity
GO Cellular Component
cell | cytoplasm | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | cytosol | intracellular
