Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for ALDH1A3;jsessionid=0E32EB2C23807C26901D46F9FAABA7E4 (gene)


Gene Symbol:
ALDH1A3 Homo sapiens Homo sapiens
Full name:
aldehyde dehydrogenase 1 family member A3
Synonyms:
ALDH1A6, ALDH6, MCOP8, RALDH3, aldehyde dehydrogenase family 1 member A3, acetaldehyde dehydrogenase 6, aldehyde dehydrogenase 6, retinaldehyde dehydrogenase 3
Genomic Location:
Chr 15: 99237532-99274354
Description:
This gene encodes an aldehyde dehydrogenase enzyme that uses retinal as a substrate. Mutations in this gene have been associated with microphthalmia, isolated 8, and expression changes have also been detected in tumor cells. Alternative splicing results in multiple transcript variants.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 15
15q26.3





GO Molecular Function

cofactor binding | nucleotide binding | coenzyme binding | NAD+ binding | catalytic activity | aldehyde dehydrogenase [NAD(P)+] activity | anion binding | thyroid hormone binding | identical protein binding | ion binding | organic cyclic compound binding | hormone binding | protein binding | protein homodimerization activity | retinal dehydrogenase activity | aldehyde dehydrogenase (NAD) activity | NAD binding | protein dimerization activity | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | heterocyclic compound binding | oxidoreductase activity | small molecule binding

GO Biological Process

brain development | protein homooligomerization | inner ear morphogenesis | reflex | positive regulation of apoptotic process | subpallium development | morphogenesis of an epithelium | isoprenoid biosynthetic process | regulation of programmed cell death | eye development | embryonic camera-type eye morphogenesis | nervous system development | neuromuscular process controlling balance | cellular process | optic cup morphogenesis involved in camera-type eye development | terpenoid biosynthetic process | tissue development | regulation of cellular process | regulation of apoptotic process | righting reflex | retinoic acid biosynthetic process | epithelium development | cellular component organization | cellular lipid metabolic process | head development | response to stimulus | monocarboxylic acid metabolic process | respiratory system development | alcohol metabolic process | retinol metabolic process | cellular component assembly | cellular biosynthetic process | embryo development | organic hydroxy compound metabolic process | retinoid metabolic process | system development | multicellular organism development | aldehyde dehydrogenase [NAD(P)+] activity | olfactory pit development | protein complex oligomerization | lipid metabolic process | regulation of hormone levels | telencephalon development | nervous system process | nucleus accumbens development | Harderian gland development | animal organ morphogenesis | striatum development | nose development | small molecule metabolic process | protein homotetramerization | embryonic camera-type eye development | biosynthetic process | locomotory behavior | lipid biosynthetic process | protein tetramerization | sensory organ development | eye morphogenesis | retinoic acid metabolic process | inner ear development | limbic system development | retinal metabolic process | embryonic morphogenesis | carboxylic acid metabolic process | cellular aldehyde metabolic process | embryonic organ morphogenesis | protein-containing complex assembly | gland development | tissue morphogenesis | retinal dehydrogenase activity | aldehyde dehydrogenase (NAD) activity | anatomical structure development | metabolic process | oxidation-reduction process | embryonic organ development | ear development | behavior | positive regulation of cell death | morphogenesis of embryonic epithelium | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | embryonic camera-type eye formation | organic substance metabolic process | animal organ development | forebrain development | positive regulation of programmed cell death | diterpenoid metabolic process | camera-type eye development | anatomical structure formation involved in morphogenesis | neuromuscular process | organic acid metabolic process | hormone metabolic process | anatomical structure morphogenesis | camera-type eye morphogenesis | isoprenoid metabolic process | developmental process | central nervous system development | cellular metabolic process | embryonic eye morphogenesis | regulation of cell death | oxidoreductase activity | ear morphogenesis | neural nucleus development | multicellular organismal process | face development

GO Cellular Component

intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | plasma membrane | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | nucleus | organelle | extracellular space | cell periphery | cytosol | intracellular | membrane