QuickView for ALKBH5;jsessionid=67C9522289817681BF6DB1685A2F24C3 (gene)
- Gene Symbol:
- ALKBH5
Homo sapiens - Full name:
- alkB homolog 5, RNA demethylase
- Synonyms:
- ABH5, OFOXD, OFOXD1, RNA demethylase ALKBH5, AlkB family member 5, RNA demethylase, alkB, alkylation repair homolog 5, alkylated DNA repair protein alkB homolog 5, alpha-ketoglutarate-dependent dioxygenase alkB homolog 5, oxoglutarate and iron-dependent oxygenase domain containing, probable alpha-ketoglutarate-dependent dioxygenase ABH5
- Genomic Location:
- Chr 17: 18027592-18053993
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Bos taurus , Danio rerio , Canis lupus familiaris , Pan troglodytes , Gallus gallus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
17p11.2::17p11.2
GO Molecular Function
oxidative RNA demethylase activity | cation binding | nucleic acid binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors | demethylase activity | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | ion binding | organic cyclic compound binding | dioxygenase activity | metal ion binding | heterocyclic compound binding | oxidoreductase activity | RNA binding
GO Biological Process
RNA metabolic process | oxidative RNA demethylase activity | RNA processing | nuclear export | establishment of localization | DNA modification | cell differentiation | male gamete generation | intracellular transport | cellular process | localization | protein transport | multicellular organismal reproductive process | macromolecule localization | response to hypoxia | establishment of localization in cell | gamete generation | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors | protein export from nucleus | RNA modification | response to stimulus | response to stress | intracellular protein transport | demethylase activity | reproduction | cellular localization | cellular nitrogen compound metabolic process | mRNA metabolic process | macromolecule modification | DNA repair | mRNA export from nucleus | response to oxygen levels | nitrogen compound metabolic process | reproductive process | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | ribonucleoprotein complex localization | cellular response to DNA damage stimulus | organic substance transport | cellular response to stress | peptide transport | RNA export from nucleus | mRNA transport | establishment of RNA localization | oxidative demethylation | protein-containing complex localization | multicellular organism reproduction | oxidative RNA demethylation | DNA metabolic process | nucleobase-containing compound transport | metabolic process | oxidation-reduction process | cellular protein localization | amide transport | nucleobase-containing compound metabolic process | organic substance metabolic process | nuclear transport | gene expression | dioxygenase activity | DNA dealkylation involved in DNA repair | establishment of protein localization | RNA transport | protein localization | cellular macromolecule localization | nucleocytoplasmic transport | developmental process | spermatogenesis | heterocycle metabolic process | demethylation | cellular metabolic process | oxidative single-stranded RNA demethylation | mRNA processing | oxidoreductase activity | RNA localization | sexual reproduction | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | nuclear body | Golgi apparatus | endomembrane system | nucleoplasm | nuclear speck | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular
