QuickView for AMOTL2 (gene)

Gene Symbol:

AMOTL2 Homo sapiens

Full name:

angiomotin like 2

Synonyms:

LCCP, angiomotin-like protein 2, Leman coiled-coil protein

Genomic Location:

Chr 3: 135556880-135576096

Description:

Angiomotin is a protein that binds angiostatin, a circulating inhibitor of the formation of new blood vessels (angiogenesis). Angiomotin mediates angiostatin inhibition of endothelial cell migration and tube formation in vitro. The protein encoded by this gene is related to angiomotin and is a member of the motin protein family. Alternative splicin...

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Angiomotin is a protein that binds angiostatin, a circulating inhibitor of the formation of new blood vessels (angiogenesis). Angiomotin mediates angiostatin inhibition of endothelial cell migration and tube formation in vitro. The protein encoded by this gene is related to angiomotin and is a member of the motin protein family. Alternative splicing results in multiple transcript variants of this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

ACAACTT_MIR382 ,  GCATTTG_MIR105 ,  GTGACTT_MIR224 ,  AACTGGA_MIR145 ,  TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  TGCCAAR_NF1_Q6 ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  GAGCCAG_MIR149 ,  CTGAGCC_MIR24

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-129 ,  Predicted Gene Targets for miR-145 ,  Predicted Gene Targets for miR-150 ,  Predicted Gene Targets for miR-200b ,  Predicted Gene Targets for miR-224 ,  Predicted Gene Targets for miR-24 ,  Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-324-3p ,  Predicted Gene Targets for miR-381 ,  Predicted Gene Targets for miR-382 ,  Predicted Gene Targets for miR-9 ,  Predicted Gene Targets for miR-96 ,  Predicted Gene Targets for miR-149 ,  Predicted Gene Targets for miR-182

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Cytogenetic Map:

3q22.2

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