QuickView for AOC3 (gene)

Gene Symbol:

AOC3 Homo sapiens

Full name:

amine oxidase, copper containing 3

Synonyms:

HPAO, SSAO, VAP-1, VAP1, membrane primary amine oxidase, amine oxidase, copper containing 3 (vascular adhesion protein 1), copper amine oxidase, placenta copper monamine oxidase, semicarbazide-sensitive amine oxidase

Genomic Location:

Chr 17: 38256727-38263667

Description:

This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leu...

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This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

HMGIY_Q6 ,  SRF_C

Cytogenetic Map:

17q21.31

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