QuickView for APELA;jsessionid=8679031F8046A262308A4B4815D196D0 (gene)

Gene Symbol:

APELA Homo sapiens

Full name:

apelin receptor early endogenous ligand

Synonyms:

ELA, Ende, tdl, apelin receptor early endogenous ligand, protein Elabela, protein Toddler

Genomic Location:

N/A

Description:

This gene encodes a peptide hormone that binds to the Apelin receptor. The encoded protein is required for heart development in zebrafish and has been shown to maintain self-renewal of human embryonic stem cells through activation of the PI3K/AKT pathway. Experiments in human and mouse cell lines point to additional roles for the encoded protein in...

View Full Description

This gene encodes a peptide hormone that binds to the Apelin receptor. The encoded protein is required for heart development in zebrafish and has been shown to maintain self-renewal of human embryonic stem cells through activation of the PI3K/AKT pathway. Experiments in human and mouse cell lines point to additional roles for the encoded protein in angiogenesis and regulation of vascular tone.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus

External Links:

Entrez Gene

search → result