QuickView for ARHGEF1;jsessionid=CFF4E6AFAB29FB0A301748A346B65437 (gene)

Gene Symbol:

ARHGEF1 Homo sapiens

Full name:

Rho guanine nucleotide exchange factor 1

Synonyms:

GEF1, LBCL2, LSC, P115-RHOGEF, SUB1.5, rho guanine nucleotide exchange factor 1, 115 kDa guanine nucleotide exchange factor, 115-kD protein, Lsc homolog, Rho guanine nucleotide exchange factor (GEF) 1, p115RhoGEF

Genomic Location:

Chr 19: 47079107-47103444

Description:

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length ...

View Full Description

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

SP1_Q4_01 ,  SP1_Q6 ,  GGGTGGRR_PAX4_03

miRNA binding sites
(Source: miRecords):

hsa-miR-124 Targeted Genes

Cytogenetic Map:

19q13.2

search → result