QuickView for ARHGEF5 (gene)

Gene Symbol:

ARHGEF5 Homo sapiens

Full name:

Rho guanine nucleotide exchange factor 5

Synonyms:

GEF5, P60, TIM, TIM1, rho guanine nucleotide exchange factor 5, Rho guanine nucleotide exchange factor (GEF) 5, ephexin-3, guanine nucleotide regulatory protein TIM, oncogene TIM, p60 TIM, transforming immortalized mammary oncogene

Genomic Location:

Chr 7: 143683422-143708658

Description:

Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization.

Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

DR3_Q4 ,  TGGNNNNNNKCCAR_UNKNOWN ,  ATGTCAC_MIR489 ,  HEB_Q6 ,  GCACCTT_MIR18A_MIR18B ,  ACCAAAG_MIR9 ,  GGCACTT_MIR519E ,  GAGCCAG_MIR149 ,  GTGGTGA_MIR197 ,  CTGAGCC_MIR24 ,  CAGCTG_AP4_Q5 ,  GTCTACC_MIR379 ,  TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-199

Cytogenetic Map:

7q35

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