QuickView for ASIC3 (gene)
- Gene Symbol:
- ASIC3
Homo sapiens - Full name:
- acid sensing ion channel subunit 3
- Synonyms:
- ACCN3, DRASIC, SLNAC1, TNaC1, acid-sensing ion channel 3, acid sensing (proton gated) ion channel 3, amiloride-sensitive cation channel 3, testis, modulatory subunit of ASIC2a, neuronal amiloride-sensitive cation channel 3, proton-gated cation channel subunit, testis sodium channel 1
- Genomic Location:
- Chr 7: 150376885-150380774
- Description:
-
This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encode...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
7q36.1
GO Molecular Function
organic anion transmembrane transporter activity | anion transmembrane transporter activity | ligand-gated sodium channel activity | siderophore transmembrane transporter activity | passive transmembrane transporter activity | transmembrane transporter activity | ligand-gated ion channel activity | ion gated channel activity | protein domain specific binding | cation transmembrane transporter activity | transporter activity | ion transmembrane transporter activity | acid-sensing ion channel activity | protein binding | metal ion transmembrane transporter activity | enterobactin transmembrane transporter activity | sodium ion transmembrane transporter activity | sodium channel activity | cation channel activity | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | PDZ domain binding | channel activity | ion channel activity | substrate-specific channel activity
GO Biological Process
response to acidic pH | detection of stimulus | enterobactin transport | organic anion transmembrane transporter activity | establishment of localization | anion transmembrane transporter activity | ligand-gated sodium channel activity | detection of mechanical stimulus involved in sensory perception | siderophore transport | sensory perception of mechanical stimulus | cellular process | siderophore transmembrane transporter activity | localization | passive transmembrane transporter activity | metal ion transport | anion transport | siderophore transmembrane transport | regulation of cellular process | transmembrane transporter activity | ligand-gated ion channel activity | response to stimulus | ion gated channel activity | response to stress | detection of chemical stimulus involved in sensory perception | sensory perception of temperature stimulus | organic hydroxy compound transport | response to temperature stimulus | response to pH | detection of temperature stimulus involved in sensory perception | detection of abiotic stimulus | detection of chemical stimulus | ion transmembrane transport | detection of mechanical stimulus involved in sensory perception of pain | organic substance transport | nervous system process | sodium ion transport | cation transmembrane transporter activity | monovalent inorganic cation transport | ion transmembrane transporter activity | acid-sensing ion channel activity | sensory perception of sour taste | sensory perception of pain | organic anion transport | detection of temperature stimulus involved in sensory perception of pain | cell communication | cation transmembrane transport | response to mechanical stimulus | detection of stimulus involved in sensory perception | metal ion transmembrane transporter activity | anion transmembrane transport | cofactor transport | enterobactin transmembrane transporter activity | sodium ion transmembrane transport | response to heat | sodium ion transmembrane transporter activity | inorganic cation transmembrane transport | sodium channel activity | detection of mechanical stimulus | cation channel activity | sensory perception | transmembrane transport | signaling | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | sensory perception of chemical stimulus | cation transport | channel activity | detection of temperature stimulus | sensory perception of taste | detection of chemical stimulus involved in sensory perception of pain | ion channel activity | ion transport | substrate-specific channel activity | signal transduction | multicellular organismal process
GO Cellular Component
integral component of membrane | cell | intrinsic component of membrane | cytoplasm | plasma membrane | integral component of plasma membrane | cell periphery | intracellular | membrane | intrinsic component of plasma membrane
