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QuickView for ATF7IP (gene)


Gene Symbol:
ATF7IP Homo sapiens Homo sapiens
Full name:
activating transcription factor 7 interacting protein
Synonyms:
AM, ATF-IP, MCAF, MCAF1, p621, activating transcription factor 7-interacting protein 1, ATF-interacting protein, ATF7-interacting protein, ATFa-associated modulator, MBD1-containing chromatin-associated factor 1
Genomic Location:
Chr 12: 14409878-14542964
Description:
ATF7IP is a multifunctional nuclear protein that associates with heterochromatin. It can act as a transcriptional coactivator or corepressor depending upon its binding partners (summary by Liu et al., 2009 [PubMed 19106100]).
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Danio rerio Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 12
12p13.1





GO Molecular Function

hydrolase activity | ATPase activity | pyrophosphatase activity | catalytic activity | nucleoside-triphosphatase activity | transcription corepressor activity | protein binding | hydrolase activity, acting on acid anhydrides | transcription coregulator activity | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

GO Biological Process

RNA metabolic process | positive regulation of macromolecule biosynthetic process | DNA modification | negative regulation of cellular process | negative regulation of RNA biosynthetic process | positive regulation of cellular biosynthetic process | regulation of transcription initiation from RNA polymerase II promoter | cellular process | negative regulation of nucleic acid-templated transcription | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | interspecies interaction between organisms | regulation of cellular process | regulation of metabolic process | regulation of protein complex assembly | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular biosynthetic process | macromolecule modification | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | regulation of gene expression | methylation | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | transcription corepressor activity | regulation of transcription by RNA polymerase II | DNA methylation | biosynthetic process | aromatic compound biosynthetic process | regulation of RNA polymerase II transcriptional preinitiation complex assembly | regulation of cellular metabolic process | regulation of RNA metabolic process | viral process | DNA metabolic process | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | gene expression | transcription, DNA-templated | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | regulation of DNA-templated transcription, initiation | negative regulation of transcription by RNA polymerase II | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | transcription coregulator activity | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | regulation of cellular component organization | positive regulation of gene expression | macromolecule metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | transcription factor complex | cytoplasm | intracellular organelle | nuclear body | protein-containing complex | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular