QuickView for ATOH1 (gene)
- Gene Symbol:
- ATOH1
Homo sapiens - Full name:
- atonal bHLH transcription factor 1
- Synonyms:
- ATH1, HATH1, MATH-1, bHLHa14, protein atonal homolog 1, atonal homolog 1, atonal homolog bHLH transcription factor 1, class A basic helix-loop-helix protein 14, helix-loop-helix protein hATH-1
- Genomic Location:
- Chr 4: 94969101-94970165
- Description:
-
This protein belongs to the basic helix-loop-helix (BHLH) family of transcription factors. It activates E-box dependent transcription along with E47.
- Orthologs:
- Mus musculus , Rattus norvegicus , C. elegans , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
4q22.2
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | proximal promoter sequence-specific DNA binding | nucleic acid binding | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | chromatin binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | chromatin DNA binding | protein dimerization activity | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | heterocyclic compound binding
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | brain development | Notch signaling pathway | cell morphogenesis | inner ear morphogenesis | positive regulation of macromolecule biosynthetic process | cell motility | regulation of neurogenesis | neuron projection morphogenesis | regulation of inner ear receptor cell differentiation | regulation of cell development | regulation of programmed cell death | neuron migration | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | positive regulation of developmental process | cell differentiation | nervous system development | positive regulation of inner ear auditory receptor cell differentiation | cell part morphogenesis | neurogenesis | generation of neurons | positive regulation of cellular biosynthetic process | cellular process | cell fate specification | localization | cell projection morphogenesis | neuron development | negative regulation of apoptotic process | axon guidance | positive regulation of nitrogen compound metabolic process | tissue development | regulation of cell differentiation | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | epithelium development | cellular aromatic compound metabolic process | cellular component organization | auditory receptor cell fate specification | head development | response to stimulus | cell morphogenesis involved in neuron differentiation | neuron projection guidance | positive regulation of epidermal cell differentiation | cellular nitrogen compound biosynthetic process | regulation of epithelial cell differentiation | cellular nitrogen compound metabolic process | inner ear receptor cell differentiation | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | positive regulation of RNA biosynthetic process | cellular biosynthetic process | embryo development | neuron fate commitment | hair cell differentiation | regulation of nucleic acid-templated transcription | locomotion | epithelial cell fate commitment | system development | nitrogen compound metabolic process | multicellular organism development | cell migration | inner ear auditory receptor cell differentiation | neuroepithelial cell differentiation | mechanoreceptor differentiation | telencephalon development | regulation of neuron differentiation | regulation of gene expression | axon development | regulation of epidermis development | auditory receptor cell fate commitment | positive regulation of cellular metabolic process | animal organ morphogenesis | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | axonogenesis | positive regulation of cell differentiation | epidermal cell differentiation | biosynthetic process | aromatic compound biosynthetic process | epidermis development | cell morphogenesis involved in differentiation | sensory organ development | cell communication | regulation of cellular metabolic process | inner ear development | regulation of RNA metabolic process | cerebral cortex development | embryonic morphogenesis | neuron differentiation | embryonic organ morphogenesis | regulation of inner ear auditory receptor cell differentiation | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | anatomical structure development | cell surface receptor signaling pathway | positive regulation of neurogenesis | cell projection organization | metabolic process | positive regulation of cell development | cell fate commitment | regulation of RNA biosynthetic process | negative regulation of programmed cell death | embryonic organ development | ear development | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | neuron projection development | organic substance metabolic process | animal organ development | forebrain development | pallium development | gene expression | transcription, DNA-templated | signaling | regulation of transcription, DNA-templated | cell development | neuron fate determination | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | positive regulation of inner ear receptor cell differentiation | regulation of nervous system development | regulation of developmental process | developmental process | positive regulation of epithelial cell differentiation | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | cell fate determination | epithelial cell differentiation | positive regulation of transcription by RNA polymerase II | positive regulation of epidermis development | heterocycle metabolic process | central nervous system development | positive regulation of metabolic process | positive regulation of neuron differentiation | cellular metabolic process | regulation of cell death | negative regulation of cell death | auditory receptor cell fate determination | neuron fate specification | chemotaxis | ear morphogenesis | regulation of epidermal cell differentiation | signal transduction | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | cell | intracellular organelle | membrane-bounded organelle | nucleus | organelle | intracellular
