QuickView for ATP6AP1;jsessionid=8D9B7F34DD72C3DD249344ED4BABA261 (gene)

Gene Symbol:

ATP6AP1 Homo sapiens

Full name:

ATPase H+ transporting accessory protein 1

Synonyms:

16A, ATP6IP1, ATP6S1, Ac45, CF2, VATPS1, XAP-3, XAP3, V-type proton ATPase subunit S1, ATPase, H+ transporting, lysosomal (vacuolar proton pump), subunit 1, ATPase, H+ transporting, lysosomal accessory protein 1, ATPase, H+ transporting, lysosomal interacting protein 1, H-ATPase subunit, V-ATPase Ac45 subunit, V-ATPase S1 accessory protein, V-ATPase subunit S1, protein XAP-3, vacuolar proton pump subunit S1

Genomic Location:

Chr X: 153310172-153318056

Description:

This gene encodes a component of a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorti...

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This gene encodes a component of a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. This protein may also play a role in early development.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TCANNTGAY_SREBP1_01 ,  IPF1_Q4 ,  TGAYRTCA_ATF3_Q6 ,  P53_02 ,  GGGCGGR_SP1_Q6

Cytogenetic Map:

Xq28

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