QuickView for ATP8B1 (gene)

Gene Symbol:

ATP8B1 Homo sapiens

Full name:

ATPase phospholipid transporting 8B1

Synonyms:

ATPIC, BRIC, FIC1, ICP1, PFIC, PFIC1, phospholipid-transporting ATPase IC, ATPase, aminophospholipid transporter, class I, type 8B, member 1, ATPase, class I, type 8B, member 1, E1-E2 ATPase, P4-ATPase flippase complex alpha subunit ATP8B1, familial intrahepatic cholestasis type 1, probable phospholipid-transporting ATPase IC

Genomic Location:

Chr 18: 53464656-53550037

Description:

This gene encodes a member of the P-type cation transport ATPase family, which belongs to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to another. Mutations in this gene may result in progressive familial intrahepatic ...

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This gene encodes a member of the P-type cation transport ATPase family, which belongs to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to another. Mutations in this gene may result in progressive familial intrahepatic cholestasis type 1 and in benign recurrent intrahepatic cholestasis.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

OCT_Q6 ,  OCT1_Q5_01 ,  WTGAAAT_UNKNOWN ,  CART1_01 ,  GGGTGGRR_PAX4_03

Cytogenetic Map:

18q21.31

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