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QuickView for Aceprometazine (compound)


PubChem
Name: aceprometazine
PubChem Compound ID: 11178444
Molecular formula: C22H21F3N2O5
Molecular weight: 450.408 g/mol
DrugBank
Identification
Name: aceprometazine
Name (isomeric): DB01615
Drug Type: small molecule
Synonyms:
Aceprometazina [inn-spanish]; Aceprometazinum [inn-latin]; 10-(2-(Dimethylamino)propyl)phenothiazin-2-yl methyl ketone; Acepromethazine
Brand: Mepronizine
Category: Sedatives and Hypnotics, Antihistamines
CAS number: 13461-01-3
Pharmacology
Indication: Aceprometazine is often used in combination with meprobamate for the treatment of sleep disorders.
Pharmacology: Aceprometazine is a drug with neuroleptic and anti-histamine properties. It is not widely prescribed.
Mechanism of Action: Aceprometazine, acting as an H1-receptor antagonist can induce sedation by being able to cross the blood-brain-barrier and binding to H1-receptors in the central nervous system.
Absorption: Rapidly absorbed following oral administration.
Biotransformation: Hepatic.
Affected organisms: Humans and other mammals
Interactions
Drug interaction:
DonepezilPossible antagonism of action
GalantaminePossible antagonism of action

Targets