QuickView for Adamts16 (gene)

Gene Symbol:

ADAMTS16 Homo sapiens

Full name:

ADAM metallopeptidase with thrombospondin type 1 motif 16

Synonyms:

ADAMTS16s, A disintegrin and metalloproteinase with thrombospondin motifs 16, ADAM-TS 16, ADAM-TS16, ADAMTS-16, a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 16

Genomic Location:

Chr 5: 5193443-5373412

Description:

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ...

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This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protein, which may inhibit chondrosarcoma cell proliferation and migration. This gene may regulate blood pressure.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Cytogenetic Map:

5p15.32

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