QuickView for AgRP (gene)

Gene Symbol:

AGRP Homo sapiens

Full name:

agouti related neuropeptide

Synonyms:

AGRT, ART, ASIP2, agouti-related protein, agouti related protein homolog

Genomic Location:

Chr 16: 66073975-66075217

Description:

This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity.

This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Bos taurus ,  Gallus gallus ,  Canis lupus familiaris ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

USF_Q6 ,  CACGTG_MYC_Q2 ,  YGACNNYACAR_UNKNOWN ,  ARNT_02 ,  GGGNRMNNYCAT_UNKNOWN ,  STAT5B_01 ,  AR_01 ,  SRF_Q4 ,  OCT1_06 ,  STAT_01 ,  USF_Q6_01 ,  TTCYNRGAA_STAT5B_01 ,  STAT5A_01

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Cytogenetic Map:

16q22.1

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