QuickView for Ambra1 (gene)
- Gene Symbol:
- AMBRA1
Homo sapiens - Full name:
- autophagy and beclin 1 regulator 1
- Synonyms:
- DCAF3, WDR94, activating molecule in BECN1-regulated autophagy protein 1, DDB1 and CUL4 associated factor 3, WD repeat domain 94, activating molecule in beclin-1-regulated autophagy, autophagy/beclin-1 regulator 1
- Genomic Location:
- Chr 11: 46374541-46569490
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
11p11.2
GO Molecular Function
GTPase binding | enzyme binding | ubiquitin-like protein ligase binding | protein binding | ubiquitin protein ligase binding
GO Biological Process
response to extracellular stimulus | response to nutrient levels | macroautophagy | regulation of programmed cell death | regulation of autophagy | negative regulation of neuron death | selective autophagy | negative regulation of cellular process | regulation of cardiac muscle cell apoptotic process | cell differentiation | nervous system development | cellular response to extracellular stimulus | positive regulation of phosphate metabolic process | autophagy of mitochondrion | regulation of neuron death | positive regulation of phosphatidylinositol 3-kinase activity | cellular process | negative regulation of apoptotic process | cellular response to starvation | positive regulation of catalytic activity | tissue development | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | catabolic process | epithelium development | cellular component organization | response to stimulus | response to stress | regulation of cell proliferation | response to starvation | cellular component assembly | embryo development | mitochondrion organization | regulation of phosphatidylinositol 3-kinase activity | negative regulation of neuron apoptotic process | organelle assembly | system development | cellular response to nutrient levels | autophagosome organization | multicellular organism development | negative regulation of striated muscle cell apoptotic process | regulation of catalytic activity | regulation of phosphorylation | cellular response to stress | positive regulation of cellular metabolic process | negative regulation of cardiac muscle cell apoptotic process | neural tube development | vacuole organization | autophagy | regulation of lipid kinase activity | regulation of muscle cell apoptotic process | chordate embryonic development | cell communication | regulation of cellular metabolic process | regulation of neuron apoptotic process | embryo development ending in birth or egg hatching | regulation of phospholipid metabolic process | organelle disassembly | positive regulation of molecular function | autophagosome assembly | regulation of kinase activity | anatomical structure development | metabolic process | negative regulation of programmed cell death | negative regulation of muscle cell apoptotic process | positive regulation of kinase activity | regulation of phosphate metabolic process | positive regulation of autophagy | mitophagy | response to mitochondrial depolarisation | positive regulation of phosphorylation | developmental process | organelle organization | tube development | negative regulation of cell proliferation | positive regulation of lipid kinase activity | regulation of lipid metabolic process | positive regulation of metabolic process | positive regulation of lipid metabolic process | cellular metabolic process | regulation of cell death | negative regulation of cell death | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | organelle membrane | cytoplasmic vesicle | cell | organelle outer membrane | cytoplasm | intracellular organelle | cell projection | plasma membrane bounded cell projection cytoplasm | cilium | vacuole | vesicle | perinuclear region of cytoplasm | cytoplasmic region | mitochondrion | axoneme | membrane-bounded organelle | organelle | mitochondrial outer membrane | mitochondrial envelope | ciliary plasm | outer membrane | mitochondrial membrane | cytosol | intracellular vesicle | cytoskeleton | endocytic vesicle | intracellular | autophagosome | membrane | phagocytic vesicle
