QuickView for Amelotin (gene)

Gene Symbol:

AMTN Homo sapiens

Full name:

amelotin

Synonyms:

AI3B, UNQ689, amelotin, RSTI689

Genomic Location:

Chr 4: 71418887-71433048

Description:

The mineralized portions of teeth, the dentin and enamel, are formed by mesenchyme-derived odontoblasts and epithelium-derived ameloblasts, respectively. As ameloblasts differentiate, they deposit specific proteins necessary for enamel formation, including amelogenin (AMELX; MIM 300391), enamelin (ENAM; MIM 606585), and ameloblastin (AMBN; MIM 6012...

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The mineralized portions of teeth, the dentin and enamel, are formed by mesenchyme-derived odontoblasts and epithelium-derived ameloblasts, respectively. As ameloblasts differentiate, they deposit specific proteins necessary for enamel formation, including amelogenin (AMELX; MIM 300391), enamelin (ENAM; MIM 606585), and ameloblastin (AMBN; MIM 601259), in the organic enamel matrix. Amelotin is specifically expressed in maturation-stage ameloblasts (Iwasaki et al., 2005 [PubMed 16304441]).

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  STAT1_02 ,  NFY_C ,  STAT1_03 ,  WTGAAAT_UNKNOWN ,  CEBP_Q2 ,  CEBPB_01 ,  TITF1_Q3 ,  TNCATNTCCYR_UNKNOWN ,  IRF_Q6 ,  CEBP_C

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Cytogenetic Map:

4q13.3

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