QuickView for Apolipoprotein L1 (gene)

Gene Symbol:

APOL1 Homo sapiens

Full name:

apolipoprotein L1

Synonyms:

APO-L, APOL, APOL-I, FSGS4, apolipoprotein L1, apolipoprotein L 1, apolipoprotein L1-B3

Genomic Location:

Chr 22: 34979070-34993523

Description:

This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play ...

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This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Macaca mulatta

External Links:

Entrez Gene

Cytogenetic Map:

22q12.3

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