QuickView for BAD;jsessionid=DED554D9C44B5B83C14C28A3F293516C (gene)

Gene Symbol:

BAD Homo sapiens

Full name:

BCL2 associated agonist of cell death

Synonyms:

BBC2, BCL2L8, bcl2-associated agonist of cell death, BCL-X/BCL-2 binding protein, BCL2-antagonist of cell death protein, BCL2-binding component 6, BCL2-binding protein, bcl-2-binding component 6, bcl-2-like protein 8, bcl-XL/Bcl-2-associated death promoter, bcl2 antagonist of cell death, bcl2-L-8

Genomic Location:

Chr 11: 63793878-63808740

Description:

The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosp...

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The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Canis lupus familiaris ,  Danio rerio ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

MAF_Q6 ,  RFX1_02 ,  SP1_Q4_01 ,  NKX62_Q2 ,  GGGCGGR_SP1_Q6 ,  RAAGNYNNCTTY_UNKNOWN ,  SP1_Q6 ,  PTF1BETA_Q6 ,  SCGGAAGY_ELK1_02 ,  YY1_02 ,  CCCNNNNNNAAGWT_UNKNOWN ,  TGACAGNY_MEIS1_01 ,  RCGCANGCGY_NRF1_Q6 ,  SP1_Q2_01 ,  GGGTGGRR_PAX4_03

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Cytogenetic Map:

11q13.1

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