QuickView for BATF (gene)
- Gene Symbol:
- BATF
Homo sapiens - Full name:
- basic leucine zipper ATF-like transcription factor
- Synonyms:
- B-ATF, BATF1, SFA-2, SFA2, basic leucine zipper transcriptional factor ATF-like, B-cell-activating transcription factor, SF-HT-activated gene 2 protein, activating transcription factor B, basic leucine zipper transcription factor, ATF-like
- Genomic Location:
- Chr 14: 75058537-75083086
- Description:
-
The protein encoded by this gene is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins. This protein is thought to be a negative regulator of AP-1/ATF transcriptional events.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Danio rerio , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
AML_Q6 , CIZ_01 , AML1_01 , RFX1_02 , STAT5B_01 , GGGCGGR_SP1_Q6 , RACCACAR_AML_Q6 , STAT_01 , HMGIY_Q6 , AML1_Q6
- Cytogenetic Map:
-
14q24.3
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | proximal promoter sequence-specific DNA binding | nucleic acid binding | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | heterocyclic compound binding
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | adaptive immune response | positive regulation of macromolecule biosynthetic process | CD4-positive, alpha-beta T cell differentiation | response to cytokine | CD4-positive, alpha-beta T cell activation | intracellular signal transduction | T cell lineage commitment | defense response to other organism | myeloid cell differentiation | RNA polymerase II transcription factor activity, sequence-specific DNA binding | T-helper cell lineage commitment | cell differentiation | defense response | T-helper 2 cell differentiation | positive regulation of cellular biosynthetic process | cellular process | lymphocyte differentiation | T-helper 17 cell differentiation | lymphoid progenitor cell differentiation | immune system development | myeloid dendritic cell differentiation | positive regulation of nitrogen compound metabolic process | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment | regulation of cellular process | leukocyte activation | regulation of metabolic process | T cell differentiation involved in immune response | type 2 immune response | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | T cell activation | response to stimulus | alpha-beta T cell activation involved in immune response | response to stress | leukocyte activation involved in immune response | cellular nitrogen compound biosynthetic process | T-helper 17 cell lineage commitment | hematopoietic progenitor cell differentiation | cellular nitrogen compound metabolic process | myeloid dendritic cell activation | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | positive regulation of RNA biosynthetic process | hemopoiesis | cellular biosynthetic process | DNA recombination | regulation of nucleic acid-templated transcription | T-helper cell differentiation | leukocyte differentiation | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | response to external biotic stimulus | system development | nitrogen compound metabolic process | DNA damage response, signal transduction by p53 class mediator | multicellular organism development | cellular response to DNA damage stimulus | leukocyte mediated immunity | somatic recombination of immunoglobulin gene segments | signal transduction in response to DNA damage | regulation of gene expression | cellular response to stress | alpha-beta T cell lineage commitment | myeloid leukocyte differentiation | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | cytokine-mediated signaling pathway | regulation of transcription by RNA polymerase II | alpha-beta T cell differentiation | stem cell differentiation | cellular response to cytokine stimulus | B cell activation | biosynthetic process | aromatic compound biosynthetic process | T cell activation involved in immune response | defense response to protozoan | cell communication | regulation of cellular metabolic process | cell activation involved in immune response | regulation of RNA metabolic process | lymphocyte activation | cytokine production | T cell differentiation | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | T cell selection | response to organic substance | DNA metabolic process | anatomical structure development | cell surface receptor signaling pathway | metabolic process | cell fate commitment | dendritic cell differentiation | immunoglobulin production involved in immunoglobulin mediated immune response | immunoglobulin production | regulation of RNA biosynthetic process | somatic diversification of immunoglobulins | positive T cell selection | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | immune response | nucleobase-containing compound metabolic process | organic substance metabolic process | animal organ development | gene expression | response to protozoan | alpha-beta T cell activation | transcription, DNA-templated | cell activation | somatic recombination of immunoglobulin genes involved in immune response | signaling | regulation of transcription, DNA-templated | B cell activation involved in immune response | somatic cell DNA recombination | cellular macromolecule biosynthetic process | response to biotic stimulus | hematopoietic stem cell differentiation | B cell mediated immunity | developmental process | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | isotype switching | immunoglobulin mediated immune response | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | cellular response to organic substance | signal transduction by p53 class mediator | response to other organism | signal transduction | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular
