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QuickView for BCHE (gene)

Gene Symbol:
BCHE Homo sapiens Homo sapiens
Full name:
CHE1, CHE2, E1, cholinesterase, acylcholine acylhydrolase, butyrylcholine esterase, choline esterase II, cholinesterase (serum) 2, cholinesterase 1, pseudocholinesterase
Genomic Location:
Chr 3: 166973386-167037947
This gene encodes a cholinesterase enzyme and member of the type-B carboxylesterase/lipase family of proteins. The encoded enzyme exhibits broad substrate specificity and is involved in the detoxification of poisons including organophosphate nerve agents and pesticides, and the metabolism of drugs including cocaine, heroin and aspirin. Humans homoz...
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 3

Transcripts Names
Protein Names

GO Molecular Function

peptide binding | amyloid-beta binding | cation binding | neurotransmitter binding | enzyme binding | carboxylic ester hydrolase activity | hydrolase activity | cholinesterase activity | choline binding | catalytic activity | amide binding | hydrolase activity, acting on ester bonds | identical protein binding | ion binding | protein binding | acetylcholinesterase activity

GO Biological Process

response to extracellular stimulus | response to nutrient levels | response to hormone | negative regulation of cellular process | cell differentiation | nervous system development | response to drug | neurogenesis | generation of neurons | response to folic acid | cellular process | alkaloid metabolic process | negative regulation of signaling | learning | regulation of cellular process | xenobiotic metabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | choline metabolic process | response to stimulus | cellular response to xenobiotic stimulus | regulation of cell proliferation | modulation of chemical synaptic transmission | regulation of neurotransmitter levels | response to nitrogen compound | system development | nitrogen compound metabolic process | multicellular organism development | learning or memory | response to lipid | nervous system process | response to corticosteroid | response to nutrient | cognition | stem cell differentiation | neurotransmitter metabolic process | response to xenobiotic stimulus | drug metabolic process | response to organic substance | anatomical structure development | metabolic process | behavior | organic substance metabolic process | response to vitamin | response to alkaloid | regulation of cell communication | cocaine metabolic process | response to organic cyclic compound | developmental process | negative regulation of cell proliferation | response to organonitrogen compound | heterocycle metabolic process | negative regulation of synaptic transmission | cellular metabolic process | response to steroid hormone | neuroblast differentiation | regulation of signaling | response to glucocorticoid | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear envelope lumen | endomembrane system | nuclear envelope | endoplasmic reticulum lumen | extracellular region | membrane-bounded organelle | nucleus | organelle | extracellular space | membrane-enclosed lumen | blood microparticle | intracellular | membrane