QuickView for BCHE (gene)

Gene Symbol:

BCHE Homo sapiens

Full name:

butyrylcholinesterase

Synonyms:

CHE1, CHE2, E1, cholinesterase, acylcholine acylhydrolase, butyrylcholine esterase, choline esterase II, cholinesterase (serum) 2, cholinesterase 1, pseudocholinesterase

Genomic Location:

Chr 3: 166973386-167037947

Description:

This gene encodes a cholinesterase enzyme and member of the type-B carboxylesterase/lipase family of proteins. The encoded enzyme exhibits broad substrate specificity and is involved in the detoxification of poisons including organophosphate nerve agents and pesticides, and the metabolism of drugs including cocaine, heroin and aspirin. Humans homoz...

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This gene encodes a cholinesterase enzyme and member of the type-B carboxylesterase/lipase family of proteins. The encoded enzyme exhibits broad substrate specificity and is involved in the detoxification of poisons including organophosphate nerve agents and pesticides, and the metabolism of drugs including cocaine, heroin and aspirin. Humans homozygous for certain mutations in this gene exhibit prolonged apnea after administration of the muscle relaxant succinylcholine.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CTTTGT_LEF1_Q2 ,  AACTTT_UNKNOWN ,  TGACATY_UNKNOWN

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-142-5p

Cytogenetic Map:

3q26.1

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