QuickView for BNIP3 (gene)

Gene Symbol:

BNIP3 Homo sapiens

Full name:

BCL2 interacting protein 3

Synonyms:

NIP3, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3, BCL2/adenovirus E1B 19kDa interacting protein 3

Genomic Location:

Chr 10: 133631194-133645425

Description:

This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation.

This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGANTCA_AP1_C ,  RSRFC4_01 ,  TGANNYRGCA_TCF11MAFG_01 ,  RSRFC4_Q2 ,  TGACCTY_ERR1_Q2 ,  TATAAA_TATA_01 ,  NFE2_01 ,  AP1_01 ,  DR1_Q3 ,  TATA_C ,  NRF2_Q4 ,  AP1_Q4 ,  BACH1_01 ,  MYOGENIN_Q6 ,  TATA_01 ,  CTTTGT_LEF1_Q2 ,  CAGCTG_AP4_Q5 ,  AP1_Q4_01 ,  TGASTMAGC_NFE2_01 ,  LBP1_Q6

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Cytogenetic Map:

10q26.3

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