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QuickView for Bcl2l13 (gene)


Gene Symbol:
BCL2L13 Homo sapiens Homo sapiens
Full name:
BCL2 like 13
Synonyms:
BCL-RAMBO, Bcl2-L-13, MIL1, bcl-2-like protein 13, BCL2-like 13 (apoptosis facilitator)
Genomic Location:
Chr 22: 16501485-16591991
Description:
This gene encodes a mitochondrially-localized protein with conserved B-cell lymphoma 2 homology motifs. Overexpression of the encoded protein results in apoptosis. Alternatively spliced transcript variants have been observed for this gene.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Canis lupus familiaris Danio rerio Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 22
22q11.21





GO Molecular Function

enzyme activator activity | peptidase activator activity | molecular function regulator | peptidase activator activity involved in apoptotic process | protein binding | cysteine-type endopeptidase regulator activity involved in apoptotic process | enzyme regulator activity | cysteine-type endopeptidase activator activity involved in apoptotic process

GO Biological Process

regulation of cysteine-type endopeptidase activity | enzyme activator activity | positive regulation of apoptotic process | regulation of programmed cell death | cellular process | regulation of proteolysis | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | peptidase activator activity | positive regulation of cellular protein metabolic process | positive regulation of protein metabolic process | positive regulation of peptidase activity | positive regulation of cysteine-type endopeptidase activity | programmed cell death | positive regulation of proteolysis | molecular function regulator | apoptotic process | regulation of peptidase activity | regulation of catalytic activity | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of cysteine-type endopeptidase activity involved in apoptotic process | peptidase activator activity involved in apoptotic process | positive regulation of hydrolase activity | regulation of cellular protein metabolic process | positive regulation of endopeptidase activity | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of molecular function | activation of cysteine-type endopeptidase activity involved in apoptotic process | positive regulation of cell death | cell death | positive regulation of programmed cell death | cysteine-type endopeptidase regulator activity involved in apoptotic process | enzyme regulator activity | regulation of endopeptidase activity | cysteine-type endopeptidase activator activity involved in apoptotic process | positive regulation of metabolic process | regulation of cell death

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | nucleus | organelle | mitochondrial envelope | mitochondrial membrane | intracellular | membrane