QuickView for C-peptide (gene)
- Gene Symbol:
- Ins2
Rattus norvegicus - Full name:
- insulin 2
- Synonyms:
- CP-II, insulin-2, C-peptide
- Genomic Location:
- Chr 1: 202935548-202936379
- Description:
-
gene encodes preproinsulin which is prossesed to form hormone involved in glucose and lipid metabolism
- Orthologs:
- Homo sapiens , Mus musculus , Bos taurus , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
cation binding | enzyme binding | protein-containing complex binding | signaling receptor binding | hormone activity | molecular function regulator | identical protein binding | ion binding | protein binding | insulin receptor binding | zinc ion binding | receptor regulator activity | receptor ligand activity | transition metal ion binding | insulin-like growth factor receptor binding | protease binding | metal ion binding
GO Biological Process
regulation of JUN kinase activity | positive regulation of glycogen biosynthetic process | protein hexamerization | regulation of cell cycle process | myoblast fusion | positive regulation of macromolecule biosynthetic process | negative regulation of immune system process | response to endoplasmic reticulum stress | positive regulation of cellular component organization | regulation of cellular localization | negative regulation of peptide secretion | positive regulation of ATP metabolic process | intracellular signal transduction | regulation of cell development | regulation of localization | syncytium formation by plasma membrane fusion | positive regulation of DNA-binding transcription factor activity | regulation of carbohydrate metabolic process | positive regulation of peptidyl-tyrosine phosphorylation | regulation of immune system process | response to hormone | negative regulation of cellular process | regulation of MAP kinase activity | negative regulation of RNA biosynthetic process | glucose metabolic process | regulation of protein localization to membrane | cell differentiation | defense response | glucose homeostasis | positive regulation of phosphate metabolic process | regulation of protein oligomerization | negative regulation of protein secretion | regulation of organelle organization | positive regulation of protein secretion | negative regulation of proteolysis | positive regulation of phosphatidylinositol 3-kinase activity | positive regulation of cellular biosynthetic process | cellular process | organic substance catabolic process | negative regulation of inflammatory response | regulation of glucose import | regulation of glycolytic process | neuron projection maintenance | negative regulation of NAD(P)H oxidase activity | canonical Wnt signaling pathway | anion homeostasis | regulation of mitotic nuclear division | negative regulation of nucleic acid-templated transcription | negative regulation of innate immune response | positive regulation of protein kinase activity | negative regulation of secretion | regulation of proteolysis | regulation of cell cycle | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | negative regulation of establishment of protein localization | negative regulation of cellular metabolic process | response to peptide hormone | regulation of behavior | regulation of binding | regulation of cell differentiation | muscle structure development | muscle cell differentiation | intrinsic apoptotic signaling pathway | negative regulation of acute inflammatory response | regulation of protein kinase B signaling | regulation of immune response | regulation of cellular process | leukocyte activation | positive regulation of insulin receptor signaling pathway | regulation of metabolic process | positive regulation of stress-activated MAPK cascade | catabolic process | regulation of protein complex assembly | positive regulation of cellular protein metabolic process | cellular response to organonitrogen compound | cellular component organization | MAPK cascade | T cell activation | regulation of peptide secretion | regulation of glycogen catabolic process | positive regulation of stress-activated protein kinase signaling cascade | response to stimulus | negative regulation of protein transport | regulation of cellular protein localization | regulation of feeding behavior | JNK cascade | regulation of peptidyl-tyrosine phosphorylation | positive regulation of protein metabolic process | signal transduction by protein phosphorylation | positive regulation of phosphatidylinositol 3-kinase signaling | response to stress | positive regulation of nitric oxide mediated signal transduction | positive regulation of cellular protein localization | regulation of cell proliferation | response to peptide | positive regulation of glucose import | programmed cell death | negative regulation of glycogen catabolic process | positive regulation of cytokine secretion | negative regulation of protein oligomerization | negative regulation of transport | hormone activity | regulation of protein transport | G-protein coupled receptor signaling pathway | negative regulation of metabolic process | positive regulation of protein serine/threonine kinase activity | cellular component assembly | protein modification process | regulation of synapse structure or activity | regulation of peptide transport | negative regulation of reactive oxygen species biosynthetic process | regulation of phosphatidylinositol 3-kinase activity | macromolecule modification | cell-cell signaling | activation of protein kinase activity | molecular function regulator | cell surface receptor signaling pathway involved in cell-cell signaling | stress-activated protein kinase signaling cascade | regulation of nucleic acid-templated transcription | positive regulation of peptide secretion | regulation of cellular response to stress | response to nitrogen compound | apoptotic process | cellular response to hormone stimulus | nitrogen compound metabolic process | regulation of signal transduction | positive regulation of organelle organization | negative regulation of secretion by cell | Wnt signaling pathway | negative regulation of respiratory burst | positive regulation of dendritic spine maintenance | negative regulation of catalytic activity | syncytium formation | cellular response to peptide hormone stimulus | regulation of MAPK cascade | phosphorus metabolic process | negative regulation of lipid catabolic process | protein complex oligomerization | cellular response to insulin stimulus | positive regulation of protein kinase B signaling | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | lipid metabolic process | ER-nucleus signaling pathway | regulation of phosphorylation | positive regulation of glucose import in response to insulin stimulus | wound healing | regulation of acute inflammatory response | positive regulation of cell cycle | positive regulation of mitotic cell cycle | regulation of gene expression | positive regulation of secretion | regulation of cellular amino acid metabolic process | cellular response to stress | cellular response to peptide | regulation of glucose import in response to insulin stimulus | insulin receptor signaling pathway | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of protein localization to nucleus | positive regulation of ATP biosynthetic process | regulation of synapse organization | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | monosaccharide metabolic process | positive regulation of JNK cascade | small molecule metabolic process | positive regulation of cell projection organization | positive regulation of intracellular signal transduction | regulation of transcription by RNA polymerase II | regulation of fatty acid metabolic process | activation of protein kinase B activity | acute-phase response | positive regulation of glucose transmembrane transport | positive regulation of glycolytic process | positive regulation of protein localization to nucleus | stress-activated MAPK cascade | regulation of cellular protein metabolic process | negative regulation of immune response | phosphorylation | carbohydrate metabolic process | protein phosphorylation | regulation of respiratory burst | phosphate-containing compound metabolic process | positive regulation of cellular response to insulin stimulus | regulation of lipid kinase activity | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of lipid catabolic process | inflammatory response | regulation of protein metabolic process | positive regulation of signal transduction | homeostatic process | positive regulation of cell proliferation | positive regulation of establishment of protein localization | regulation of protein phosphorylation | regulation of RNA metabolic process | positive regulation of transport | regulation of phospholipid metabolic process | striated muscle cell differentiation | apoptotic signaling pathway | ER overload response | regulation of mitotic cell cycle | lymphocyte activation | positive regulation of molecular function | regulation of cytokine secretion | activation of MAPK activity | regulation of signaling receptor activity | receptor regulator activity | protein-containing complex assembly | negative regulation of carbohydrate metabolic process | protein metabolic process | regulation of establishment of protein localization | positive regulation of protein modification process | response to organic substance | regulation of innate immune response | negative regulation of behavior | positive regulation of respiratory burst | regulation of kinase activity | response to wounding | fatty acid homeostasis | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | response to insulin | anatomical structure development | cell surface receptor signaling pathway | regulation of glucose metabolic process | negative regulation of lipid metabolic process | cell projection organization | metabolic process | negative regulation of feeding behavior | positive regulation of glucose metabolic process | regulation of protein catabolic process | regulation of protein localization to plasma membrane | regulation of RNA biosynthetic process | hexose metabolic process | negative regulation of transcription, DNA-templated | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | chemical homeostasis | regulation of secretion | receptor ligand activity | lipid catabolic process | negative regulation of protein complex assembly | organic substance metabolic process | cell death | negative regulation of biosynthetic process | negative regulation of gene expression | regulation of glucose transmembrane transport | regulation of insulin receptor signaling pathway | negative regulation of cellular protein metabolic process | positive regulation of NF-kappaB transcription factor activity | regulation of protein secretion | positive regulation of kinase activity | alpha-beta T cell activation | ion homeostasis | regulation of cellular response to insulin stimulus | regulation of ATP metabolic process | regulation of phosphate metabolic process | regulation of dendritic spine maintenance | positive regulation of cytokine production | regulation of postsynapse organization | regulation of JNK cascade | cell activation | positive regulation of MAPK cascade | positive regulation of protein transport | regulation of reactive oxygen species biosynthetic process | anatomical structure formation involved in morphogenesis | negative regulation of protein catabolic process | negative regulation of protein metabolic process | positive regulation of carbohydrate metabolic process | regulation of stress-activated MAPK cascade | regulation of cell communication | negative regulation of molecular function | signaling | regulation of transcription, DNA-templated | regulation of oxidoreductase activity | regulation of protein binding | myotube differentiation | regulation of transmembrane transporter activity | positive regulation of phosphorylation | cellular protein metabolic process | regulation of cytokine production | anatomical structure morphogenesis | positive regulation of MAP kinase activity | response to biotic stimulus | regulation of cellular ketone metabolic process | regulation of developmental process | regulation of NAD(P)H oxidase activity | developmental process | positive regulation of cell cycle process | cellular protein modification process | negative regulation of transcription by RNA polymerase II | regulation of transport | regulation of reactive oxygen species metabolic process | negative regulation of oxidoreductase activity | positive regulation of lipid kinase activity | response to organonitrogen compound | regulation of glycogen biosynthetic process | positive regulation of JUN kinase activity | transmembrane receptor protein tyrosine kinase signaling pathway | regulation of generation of precursor metabolites and energy | regulation of lipid metabolic process | positive regulation of metabolic process | regulation of nitric oxide mediated signal transduction | positive regulation of lipid metabolic process | regulation of cell projection organization | acute inflammatory response | immune system process | cellular metabolic process | cellular response to organic substance | regulation of protein localization | activation of JUN kinase activity | negative regulation of respiratory burst involved in inflammatory response | regulation of inflammatory response | carbohydrate homeostasis | lipid homeostasis | regulation of cellular component organization | negative regulation of reactive oxygen species metabolic process | positive regulation of signaling | negative regulation of fatty acid metabolic process | positive regulation of mitotic nuclear division | signal transduction | regulation of phosphatidylinositol 3-kinase signaling | regulation of signaling | positive regulation of gene expression | regulation of glycogen metabolic process | macromolecule metabolic process | regulation of phosphorus metabolic process
GO Cellular Component
secretory granule | intracellular membrane-bounded organelle | cytoplasmic vesicle | cell | cytoplasm | intracellular organelle | protein-containing complex | secretory vesicle | endomembrane system | ribonucleoprotein complex | vesicle | extracellular region | membrane-bounded organelle | nucleus | organelle | extracellular space | cytosol | intracellular vesicle | intracellular | small nucleolar ribonucleoprotein complex
