QuickView for C1qA (gene)

Gene Symbol:

C1QA Homo sapiens

Full name:

complement C1q A chain

Synonyms:

complement C1q subcomponent subunit A, complement C1q chain A, complement component 1, q subcomponent, A chain, complement component 1, q subcomponent, alpha polypeptide, complement component C1q, A chain

Genomic Location:

Chr 1: 22835705-22838762

Description:

This gene encodes the A-chain polypeptide of serum complement subcomponent C1q, which associates with C1r and C1s to yield the first component of the serum complement system. C1q deficiency is associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains which include 6 A-chains, 6 B-chains, and 6 C-chains. Ea...

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This gene encodes the A-chain polypeptide of serum complement subcomponent C1q, which associates with C1r and C1s to yield the first component of the serum complement system. C1q deficiency is associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains which include 6 A-chains, 6 B-chains, and 6 C-chains. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. Alternate splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

HNF3ALPHA_Q6 ,  E2A_Q2 ,  GGGAGGRR_MAZ_Q6 ,  TAL1BETAE47_01 ,  CAGGTG_E12_Q6 ,  AREB6_01 ,  TAATTA_CHX10_01 ,  MYOGENIN_Q6 ,  ELF1_Q6

Cytogenetic Map:

1p36.12

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