QuickView for C5AR2;jsessionid=53CA6A2F744C5C7317278616728B444B (gene)

Gene Symbol:

C5AR2 Homo sapiens

Full name:

complement component 5a receptor 2

Synonyms:

C5L2, GPF77, GPR77, C5a anaphylatoxin chemotactic receptor 2, C5a anaphylatoxin chemotactic receptor C5L2, G protein-coupled receptor 77, G protein-coupled receptor C5L2

Genomic Location:

Chr 19: 52532211-52537112

Description:

This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act a...

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This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Pan troglodytes ,  Bos taurus ,  Canis lupus familiaris

External Links:

Entrez Gene

Cytogenetic Map:

19q13.32

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