QuickView for CA11;jsessionid=4A73394A07594DA78627C8C96510263F (gene)

Gene Symbol:

CA11 Homo sapiens

Full name:

carbonic anhydrase 11

Synonyms:

CARPX1, carbonic anhydrase-related protein 11, CA-RP II, CA-XI, CARP XI, CARP-2, carbonic anhydrase XI, carbonic anhydrase-related protein 2, carbonic anhydrase-related protein XI

Genomic Location:

Chr 19: 53833084-53841263

Description:

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show...

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Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XI is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. CA XI is most abundantly expressed in brain, and may play a general role in the central nervous system.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Canis lupus familiaris ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AACWWCAANK_UNKNOWN ,  NGFIC_01 ,  VDR_Q6 ,  EGR2_01 ,  WTGAAAT_UNKNOWN ,  TGCGCANK_UNKNOWN ,  RRAGTTGT_UNKNOWN ,  ACTAYRNNNCCCR_UNKNOWN ,  ACTWSNACTNY_UNKNOWN ,  AR_Q2 ,  WCAANNNYCAG_UNKNOWN ,  CAGCTG_AP4_Q5 ,  P300_01 ,  GGGTGGRR_PAX4_03

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Cytogenetic Map:

19q13.33

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