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QuickView for CACNB3 (gene)


Gene Symbol:
CACNB3 Homo sapiens Homo sapiens
Full name:
calcium voltage-gated channel auxiliary subunit beta 3
Synonyms:
CAB3, CACNLB3, voltage-dependent L-type calcium channel subunit beta-3, calcium channel, voltage-dependent, beta 3 subunit
Genomic Location:
Chr 12: 47498779-47508991
Description:
This gene encodes a regulatory beta subunit of the voltage-dependent calcium channel. Beta subunits are composed of five domains, which contribute to the regulation of surface expression and gating of calcium channels and may also play a role in the regulation of transcription factors and calcium transport.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Pan troglodytes Canis lupus familiaris Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 12
12q13.12





GO Molecular Function

kinase binding | high voltage-gated calcium channel activity | voltage-gated ion channel activity | channel regulator activity | passive transmembrane transporter activity | protein kinase binding | enzyme binding | transmembrane transporter activity | ion gated channel activity | molecular function regulator | voltage-gated calcium channel activity | cation transmembrane transporter activity | transporter activity | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | protein binding | calcium channel regulator activity | metal ion transmembrane transporter activity | voltage-gated cation channel activity | cation channel activity | inorganic cation transmembrane transporter activity | voltage-gated channel activity | channel activity | calcium channel activity | ion channel activity | substrate-specific channel activity

GO Biological Process

response to extracellular stimulus | cellular response to decreased oxygen levels | regulation of intracellular protein transport | response to nutrient levels | detection of stimulus | positive regulation of ion transmembrane transporter activity | protein localization to cell periphery | regulation of cellular localization | cytosolic calcium ion transport | regulation of localization | negative regulation of voltage-gated calcium channel activity | high voltage-gated calcium channel activity | positive regulation of voltage-gated calcium channel activity | establishment of localization | regulation of protein localization to membrane | detection of mechanical stimulus involved in sensory perception | cellular response to extracellular stimulus | cellular chemical homeostasis | positive regulation of cation channel activity | voltage-gated ion channel activity | sensory perception of mechanical stimulus | positive regulation of neurological system process | cellular process | channel regulator activity | localization | cellular homeostasis | positive regulation of synaptic transmission | passive transmembrane transporter activity | metal ion transport | chemical synaptic transmission | macromolecule localization | calcium ion transmembrane transport via high voltage-gated calcium channel | establishment of localization in cell | regulation of neurological system process | regulation of cellular process | regulation of cytosolic calcium ion concentration | transmembrane transporter activity | cellular component organization | calcium ion homeostasis | calcium ion transport into cytosol | response to stimulus | ion gated channel activity | regulation of cellular protein localization | negative regulation of neurological system process | positive regulation of cation transmembrane transport | positive regulation of cellular protein localization | regulation of high voltage-gated calcium channel activity | negative regulation of transporter activity | cellular localization | divalent metal ion transport | negative regulation of transport | regulation of protein transport | regulation of peptide transport | modulation of chemical synaptic transmission | cell-cell signaling | negative regulation of calcium ion transmembrane transport | negative regulation of transmembrane transport | regulation of intracellular transport | molecular function regulator | metal ion homeostasis | regulation of membrane potential | voltage-gated calcium channel activity | detection of abiotic stimulus | regulation of membrane hyperpolarization | cellular response to nutrient levels | response to oxygen levels | regulation of signal transduction | modulation of excitatory postsynaptic potential | positive regulation of calcium ion transmembrane transport | calcium ion transmembrane transport | ion transmembrane transport | protein localization to plasma membrane | detection of mechanical stimulus involved in sensory perception of pain | protein localization to membrane | nervous system process | synaptic signaling | cation transmembrane transporter activity | positive regulation of intracellular protein transport | neuromuscular junction development | cellular ion homeostasis | positive regulation of ion transmembrane transport | cellular response to oxygen levels | positive regulation of cytosolic calcium ion concentration | calcium ion transmembrane transporter activity | synapse organization | ion transmembrane transporter activity | negative regulation of ion transmembrane transport | negative regulation of calcium ion transmembrane transporter activity | sensory perception of pain | negative regulation of ion transport | regulation of calcium ion transmembrane transport | regulation of voltage-gated calcium channel activity | cation homeostasis | cellular cation homeostasis | cell communication | positive regulation of protein localization to membrane | negative regulation of cation channel activity | positive regulation of transporter activity | negative regulation of calcium ion transport | positive regulation of signal transduction | cellular calcium ion homeostasis | homeostatic process | positive regulation of establishment of protein localization | positive regulation of transport | negative regulation of detection of mechanical stimulus involved in sensory perception of touch | positive regulation of molecular function | cation transmembrane transport | calcium channel regulator activity | regulation of establishment of protein localization | response to mechanical stimulus | detection of stimulus involved in sensory perception | metal ion transmembrane transporter activity | voltage-gated cation channel activity | regulation of protein targeting | cellular protein localization | chemical homeostasis | calcium ion transport | membrane depolarization | negative regulation of ion transmembrane transporter activity | positive regulation of ion transport | ion homeostasis | inorganic cation transmembrane transport | regulation of ion transmembrane transport | detection of mechanical stimulus | positive regulation of intracellular transport | positive regulation of excitatory postsynaptic potential | positive regulation of protein transport | cation channel activity | sensory perception | regulation of action potential | regulation of cell communication | negative regulation of molecular function | transmembrane transport | signaling | inorganic cation transmembrane transporter activity | positive regulation of calcium ion transmembrane transporter activity | regulation of transmembrane transporter activity | protein localization | regulation of ion transmembrane transporter activity | voltage-gated channel activity | cation transport | cellular macromolecule localization | channel activity | regulation of ion transport | calcium channel activity | regulation of calcium ion transport | positive regulation of protein targeting to membrane | regulation of transport | regulation of cation channel activity | cellular metal ion homeostasis | regulation of membrane repolarization during action potential | ion channel activity | regulation of calcium ion transmembrane transporter activity | ion transport | regulation of protein localization | divalent inorganic cation homeostasis | substrate-specific channel activity | cellular response to oxygen-glucose deprivation | regulation of membrane repolarization | positive regulation of calcium ion transport | positive regulation of signaling | regulation of signaling | positive regulation of high voltage-gated calcium channel activity | multicellular organismal process

GO Cellular Component

integral component of membrane | sarcolemma | apical plasma membrane | voltage-gated calcium channel complex | cell | plasma membrane protein complex | intrinsic component of membrane | cytoplasm | apical part of cell | protein-containing complex | plasma membrane | T-tubule | calcium channel complex | cell periphery | L-type voltage-gated calcium channel complex | transmembrane transporter complex | cation channel complex | ion channel complex | cytosol | intracellular | membrane