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QuickView for CACNG8;jsessionid=B4DD9833B4210E4615D8CB5F802E36CD (gene)


Gene Symbol:
CACNG8 Homo sapiens Homo sapiens
Full name:
calcium voltage-gated channel auxiliary subunit gamma 8
Synonyms:
voltage-dependent calcium channel gamma-8 subunit, TARP gamma-8, calcium channel, voltage-dependent, gamma subunit 8, neuronal voltage-gated calcium channel gamma-8 subunit, transmembrane AMPAR regulatory protein gamma-8
Genomic Location:
Chr 19: 59158106-59177951
Description:
The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type II TARP and...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 19
19q13.42


Transcripts Names
NM_031895
Protein Names
Q9BXT0
Q9BY23
Q8WXS5



GO Molecular Function

voltage-gated ion channel activity | channel regulator activity | passive transmembrane transporter activity | transmembrane transporter activity | ion gated channel activity | molecular function regulator | voltage-gated calcium channel activity | cation transmembrane transporter activity | transporter activity | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | calcium channel regulator activity | metal ion transmembrane transporter activity | voltage-gated cation channel activity | cation channel activity | inorganic cation transmembrane transporter activity | voltage-gated channel activity | channel activity | calcium channel activity | ion channel activity | substrate-specific channel activity

GO Biological Process

regulation of AMPA receptor activity | protein localization to vacuole | regulation of localization | establishment of localization | neurotransmitter receptor internalization | voltage-gated ion channel activity | membrane organization | intracellular transport | cellular process | channel regulator activity | localization | positive regulation of synaptic transmission | protein transport | passive transmembrane transporter activity | metal ion transport | macromolecule localization | establishment of localization in cell | regulation of cellular process | transmembrane transporter activity | cellular component organization | lysosomal transport | ion gated channel activity | postsynaptic neurotransmitter receptor diffusion trapping | intracellular protein transport | vacuolar transport | neurotransmitter receptor transport | regulation of neurotransmitter receptor activity | neurotransmitter receptor transport, postsynaptic endosome to lysosome | cellular localization | divalent metal ion transport | modulation of chemical synaptic transmission | positive regulation of synaptic transmission, glutamatergic | molecular function regulator | voltage-gated calcium channel activity | regulation of signal transduction | regulation of synaptic transmission, glutamatergic | calcium ion transmembrane transport | protein transport within lipid bilayer | protein localization to lysosome | ion transmembrane transport | localization within membrane | endosome to lysosome transport | organic substance transport | nervous system process | cation transmembrane transporter activity | peptide transport | vesicle-mediated transport | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | protein localization to organelle | receptor localization to synapse | cell communication | receptor internalization | protein-containing complex localization | cation transmembrane transport | calcium channel regulator activity | regulation of signaling receptor activity | import into cell | metal ion transmembrane transporter activity | establishment of protein localization to organelle | voltage-gated cation channel activity | metabolic process | cellular protein localization | amide transport | calcium ion transport | endocytosis | organic substance metabolic process | establishment of protein localization to vacuole | inorganic cation transmembrane transport | regulation of ion transmembrane transport | establishment of protein localization | cation channel activity | regulation of cell communication | transmembrane transport | signaling | inorganic cation transmembrane transporter activity | regulation of transmembrane transporter activity | protein localization | regulation of ion transmembrane transporter activity | voltage-gated channel activity | cation transport | cellular macromolecule localization | channel activity | regulation of ion transport | receptor-mediated endocytosis | calcium channel activity | regulation of transport | receptor metabolic process | regulation of cation channel activity | transmission of nerve impulse | regulation of glutamate receptor signaling pathway | ion channel activity | ion transport | cellular metabolic process | substrate-specific channel activity | positive regulation of signaling | regulation of signaling | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

integral component of membrane | sarcolemma | synapse | endocytic vesicle membrane | organelle membrane | postsynaptic specialization membrane | cytoplasmic vesicle | voltage-gated calcium channel complex | cell | plasma membrane protein complex | intrinsic component of membrane | synaptic membrane | cytoplasm | intracellular organelle | receptor complex | protein-containing complex | postsynaptic membrane | postsynapse | plasma membrane | postsynaptic density membrane | vesicle | postsynaptic density | asymmetric synapse | integral component of plasma membrane | T-tubule | calcium channel complex | membrane-bounded organelle | organelle | postsynaptic specialization | vesicle membrane | cell periphery | L-type voltage-gated calcium channel complex | ionotropic glutamate receptor complex | transmembrane transporter complex | cation channel complex | ion channel complex | intracellular vesicle | endocytic vesicle | intracellular | cell junction | membrane | cytoplasmic vesicle membrane | AMPA glutamate receptor complex | intrinsic component of plasma membrane