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QuickView for CALHM1 (gene)


Gene Symbol:
CALHM1 Homo sapiens Homo sapiens
Full name:
calcium homeostasis modulator 1
Synonyms:
FAM26C, calcium homeostasis modulator protein 1, family with sequence similarity 26, member C
Genomic Location:
Chr 10: 105203134-105208635
Description:
This gene encodes a calcium channel that plays a role in processing of amyloid-beta precursor protein. A polymorphism at this locus has been reported to be associated with susceptibility to late-onset Alzheimer's disease in some populations, but the pathogenicity of this polymorphism is unclear.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 10
10q24.33


Transcripts Names
NM_001001412
Protein Names
Q8IU99
Q5W091



GO Molecular Function

voltage-gated ion channel activity | passive transmembrane transporter activity | transmembrane transporter activity | ion gated channel activity | voltage-gated calcium channel activity | cation transmembrane transporter activity | transporter activity | calcium ion transmembrane transporter activity | identical protein binding | ion transmembrane transporter activity | protein binding | metal ion transmembrane transporter activity | voltage-gated cation channel activity | cation channel activity | inorganic cation transmembrane transporter activity | voltage-gated channel activity | channel activity | calcium activated cation channel activity | calcium channel activity | ion channel activity | substrate-specific channel activity

GO Biological Process

protein homooligomerization | purine nucleotide transport | regulation of localization | establishment of localization | sensory perception of umami taste | response to drug | voltage-gated ion channel activity | cellular process | localization | passive transmembrane transporter activity | metal ion transport | anion transport | transmembrane transporter activity | purine ribonucleotide transport | cellular component organization | response to stimulus | ion gated channel activity | divalent metal ion transport | sensory perception of bitter taste | cellular component assembly | voltage-gated calcium channel activity | calcium ion transmembrane transport | protein complex oligomerization | ion transmembrane transport | organic substance transport | nervous system process | cation transmembrane transporter activity | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | ATP transport | organic anion transport | adenine nucleotide transport | cation transmembrane transport | protein-containing complex assembly | metal ion transmembrane transporter activity | nucleobase-containing compound transport | voltage-gated cation channel activity | calcium ion transport | inorganic cation transmembrane transport | regulation of ion transmembrane transport | drug transport | sensory perception of sweet taste | cation channel activity | sensory perception | transmembrane transport | inorganic cation transmembrane transporter activity | sensory perception of chemical stimulus | voltage-gated channel activity | cation transport | channel activity | regulation of ion transport | calcium activated cation channel activity | calcium channel activity | sensory perception of taste | regulation of transport | ion channel activity | ion transport | substrate-specific channel activity | carbohydrate derivative transport | multicellular organismal process

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | plasma membrane | integral component of plasma membrane | membrane-bounded organelle | organelle | cell periphery | intracellular | membrane | intrinsic component of plasma membrane